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Altered gut microbiota in patients with small intestinal bacterial overgrowth.
http://hdl.handle.net/10422/00013468
http://hdl.handle.net/10422/000134682aba0e94-45dd-41ac-a025-1daac687553e
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
jgh.16013 (1.8 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2022-12-08 | |||||
| タイトル | ||||||
| タイトル | Altered gut microbiota in patients with small intestinal bacterial overgrowth. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Intestinal disorders | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Small bowel | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Clinical intestinal disorders | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
BAMBA, Shigeki
× BAMBA, Shigeki× IMAI, Takayuki× SASAKI, Masaya× OHNO, Masashi× YOSHIDA, Shinya× NISHIDA, Atsushi× TAKAHASHI, Kenichiro× INATOMI, Osamu× ANDOH, Akira |
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| 著者別名 |
馬場, 重樹
× 馬場, 重樹× 今井, 隆行× 佐々木, 雅也× 大野, 将司× 吉田, 晋也× 西田, 淳史× 高橋, 憲一郎× 稲富, 理× 安藤, 朗 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background and aim: Small intestinal bacterial overgrowth (SIBO) is diagnosed by using quantitative culture of duodenal aspirates and/or a hydrogen breath test. However, few studies have analyzed bacterial microbiota in Japanese patients with SIBO. |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Methods: Twenty-four patients with any abdominal symptoms and suspected SIBO were enrolled. Quantitative culture of duodenal aspirates and a glucose hydrogen breath test were performed on the same day. SIBO was diagnosed based on a bacterial count ≥ 103 CFU/mL or a rise in the hydrogen breath level of ≥ 20 ppm. The composition of the duodenal microbiota was analyzed by 16S rRNA gene sequencing. |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Results: Small intestinal bacterial overgrowth was diagnosed in 17 of the 24 patients (71%). The positive rates for the hydrogen breath test and quantitative culture of duodenal aspirates were 50% and 62%, respectively. Patients with SIBO showed significantly reduced α-diversity compared with non-SIBO patients, and analysis of β-diversity revealed significantly different distributions between SIBO and non-SIBO patients. In addition, the intestinal microbiome in SIBO patients was characterized by increased relative abundance of Streptococcus and decreased relative abundance of Bacteroides compared with non-SIBO patients. |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Conclusions: Duodenal dysbiosis was identified in patients with SIBO and may play a role in the pathophysiology of SIBO. |
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| 書誌情報 |
en : Journal of gastroenterology and hepatology 発行日 2022-09-30 |
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| 出版者 | ||||||
| 出版者 | John Wiley and Sons Inc | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1440-1746 | |||||
| PMID | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 36180941 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1111/jgh.16013 | |||||
| 関連名称 | 10.1111/jgh.16013 | |||||
| 権利 | ||||||
| 権利情報 | © 2022 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Journal Article | |||||
