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Five of 6 patients (83%) died within 30 days after surgery. The risk-adjusted hazard ratio (95% confidence interval) for mortality per 1 SD (0.41-unit) increase in log-transformed preoperative lactate level (equivalent to a 4.10-fold increase) was 2.85 (1.57 to 5.19). Patients with lactate 5 to 10 mmol/L had 3.95-fold and those with lactate \u003e10 mmol/L had 6.03-fold higher risk of mortality than those with lactate \u003c5 mmol/L. ", "subitem_description_type": "Abstract"}, {"subitem_description": "Conclusion:\nElevation of preoperative serum lactate is significantly associated with mortality in patients who underwent VSR repair. The findings of this study highlight the value of measuring lactate level for risk stratification. 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Hyperlactatemia as a Risk Stratification for Postinfarction Ventricular Septal Rupture.
http://hdl.handle.net/10422/00013374
http://hdl.handle.net/10422/000133746833eb0a-71d9-4e40-b25f-0c1f626adca0
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2022-07-21 | |||||
タイトル | ||||||
タイトル | Hyperlactatemia as a Risk Stratification for Postinfarction Ventricular Septal Rupture. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Postinfarction Ventricular Septal Rupture | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | hyperlactatemia | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
KINOSHITA, Takeshi
× KINOSHITA, Takeshi× ASAI, Tohru× SUZUKI, Tomoaki |
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著者別名 |
木下, 武
× 木下, 武× 鈴木, 友彰 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: Surgical repair for postinfarction ventricular septal rupture (VSR) is a challenging operation, especially in the acute phase with unstable hemodynamics. We retrospectively examined the value of measuring lactate, which can be a quantitative indicator of end-organ ischemia caused by multiple factors including ineffective cardiac output, for risk stratification in patients undergoing surgical repair. |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Methods: From April 2008 to December 2018, 33 consecutive patients were admitted to our hospital with a diagnosis of VSR and underwent VSR repair surgery within 24 hours of admission. We categorized patients into 3 groups based on the distribution of preoperative blood lactate level: <5 mmol/L (n = 16), 5 to 10 mmol/L (n = 11), and >10 mmol/L (n = 6). |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Results: There was no intraoperative death, but the prognosis for patients with lactate >10 mmol/L was extremely poor, with a median postoperative survival time of only 23 days [25th percentile 6, 75th percentile 30]. Five of 6 patients (83%) died within 30 days after surgery. The risk-adjusted hazard ratio (95% confidence interval) for mortality per 1 SD (0.41-unit) increase in log-transformed preoperative lactate level (equivalent to a 4.10-fold increase) was 2.85 (1.57 to 5.19). Patients with lactate 5 to 10 mmol/L had 3.95-fold and those with lactate >10 mmol/L had 6.03-fold higher risk of mortality than those with lactate <5 mmol/L. |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Conclusion: Elevation of preoperative serum lactate is significantly associated with mortality in patients who underwent VSR repair. The findings of this study highlight the value of measuring lactate level for risk stratification. |
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書誌情報 |
en : The heart surgery forum 巻 25, 号 3, p. E345-E352, 発行日 2022-05-25 |
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出版者 | ||||||
出版者 | Forum Multimedia Pub | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1522-6662 | |||||
PMID | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 35787770 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1532/hsf.4479 | |||||
関連名称 | 10.1532/hsf.4479 | |||||
権利 | ||||||
権利情報 | © 2022 Forum Multimedia Publishing, LLC | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | ||||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal Article |