{"_buckets": {"deposit": "d6d5286f-7b8a-4c4f-9927-d88f439218b2"}, "_deposit": {"created_by": 11, "id": "4147", "owners": [11], "pid": {"revision_id": 0, "type": "depid", "value": "4147"}, "status": "published"}, "_oai": {"id": "oai:shiga-med.repo.nii.ac.jp:00004147", "sets": ["230"]}, "author_link": ["173", "7995", "7996", "6088"], "item_4_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2022-02-18", "bibliographicIssueDateType": "Issued"}, "bibliographicPageStart": "2184923221081701", "bibliographic_titles": [{}, {"bibliographic_title": "Asian cardiovascular \u0026 thoracic annals", "bibliographic_titleLang": "en"}]}]}, "item_4_creator_3": {"attribute_name": "著者別名", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "岡本, 圭伍"}], "nameIdentifiers": [{"nameIdentifier": "7995", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "000-0002-6992-3765", "nameIdentifierScheme": "ORCID", "nameIdentifierURI": "https://orcid.org/000-0002-6992-3765"}]}, {"creatorNames": [{"creatorName": "賀来, 良輔"}], "nameIdentifiers": [{"nameIdentifier": "7996", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "大塩, 恭彦"}], "nameIdentifiers": [{"nameIdentifier": "6088", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60731916", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=60731916"}]}, {"creatorNames": [{"creatorName": "花岡, 淳"}], "nameIdentifiers": [{"nameIdentifier": "173", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "00452243", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=00452243"}, {"nameIdentifier": "0000-0002-5272-556X", "nameIdentifierScheme": "ORCID", "nameIdentifierURI": "https://orcid.org/0000-0002-5272-556X"}]}]}, "item_4_description_14": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_description": "pdf", "subitem_description_type": "Other"}]}, "item_4_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Background:\nAdjuvant tegafur-uracil therapy has prolonged postoperative survival in patients with non-small cell lung cancer. Some patients experience treatment discontinuation due to gastrointestinal disorders such as anorexia, and the associated factors and the impact of lobectomy remain unclear. This study aimed to assess the postoperative esophageal displacement after lobectomy and to clarify its impact on the continuity of tegafur-uracil treatment. ", "subitem_description_type": "Abstract"}, {"subitem_description": "Methods:\nPatients who received adjuvant tegafur-uracil therapy after lobectomy between April 2009 and March 2019 were retrospectively analyzed. Patient background, perioperative characteristics, treatment findings, and the degree of esophageal displacement measured by computed tomography were compared between the treatment completion group and the discontinuation group. A subgroup comparative analysis was further performed in the groups divided according to the degree of esophageal displacement. ", "subitem_description_type": "Abstract"}, {"subitem_description": "Results:\nA total of 68 patients were reviewed, including 41 males and 27 females with a mean age of 66.2 years old. A total of 41 patients completed the 2-year adjuvant treatment and 27 patients discontinued it. The overall survival and relapse-free survival between the two groups were statistically significant (p = 0.027, p = 0.010). The degree of esophageal displacement at the Th7 level was a significant predictor of treatment discontinuation (p = 0.046, odds ratio [OR]: 1.138, 95% confidence interval [CI]: 1.002-1.291). Among the patients with a high degree of esophageal displacement above the baseline determined from the receiver operating characteristic curve, the cause of discontinuation was anorexia, which was significant in multivariate analysis (p = 0.013, OR: 14.72, 95% CI: 1.745-124.2). ", "subitem_description_type": "Abstract"}, {"subitem_description": "Conclusions:\nOur study suggested that anatomical displacement of the esophagus after lobectomy may affect the discontinuation of oral adjuvant chemotherapy in patients with lung cancer. ", "subitem_description_type": "Abstract"}]}, "item_4_description_42": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"subitem_description": "Journal Article", "subitem_description_type": "Other"}]}, "item_4_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "SAGE"}]}, "item_4_relation_10": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "35179062", "subitem_relation_type_select": "PMID"}}]}, "item_4_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1177/02184923221081701"}], "subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1177/02184923221081701", "subitem_relation_type_select": "DOI"}}]}, "item_4_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1816-5370", "subitem_source_identifier_type": "ISSN"}]}, "item_4_version_type_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "OKAMOTO, Keigo"}], "nameIdentifiers": [{"nameIdentifier": "7995", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "000-0002-6992-3765", "nameIdentifierScheme": "ORCID", "nameIdentifierURI": "https://orcid.org/000-0002-6992-3765"}]}, {"creatorNames": [{"creatorName": "KAKU, Ryosuke"}], "nameIdentifiers": [{"nameIdentifier": "7996", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "OSHIO, Yasuhiko"}], "nameIdentifiers": [{"nameIdentifier": "6088", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60731916", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=60731916"}]}, {"creatorNames": [{"creatorName": "HANAOKA, Jun"}], "nameIdentifiers": [{"nameIdentifier": "173", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "00452243", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=00452243"}, {"nameIdentifier": "0000-0002-5272-556X", "nameIdentifierScheme": "ORCID", "nameIdentifierURI": "https://orcid.org/0000-0002-5272-556X"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2022-03-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "02184923221081701.pdf", "filesize": [{"value": "944.7 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 944700.0, "url": {"label": "02184923221081701", "url": "https://shiga-med.repo.nii.ac.jp/record/4147/files/02184923221081701.pdf"}, "version_id": "f96a4316-1f01-4720-9ace-f5c9b4a0060d"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Lung cancer", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "tegafur-uracil", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "adjuvant chemotherapy", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "surgical mortality", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "mediastinal shift: esophageal displacement", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Impact of thoracic esophageal displacement after lobectomy on the continuity of oral adjuvant chemotherapy.", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Impact of thoracic esophageal displacement after lobectomy on the continuity of oral adjuvant chemotherapy."}]}, "item_type_id": "4", "owner": "11", "path": ["230"], "permalink_uri": "http://hdl.handle.net/10422/00013239", "pubdate": {"attribute_name": "公開日", "attribute_value": "2022-03-24"}, "publish_date": "2022-03-24", "publish_status": "0", "recid": "4147", "relation": {}, "relation_version_is_last": true, "title": ["Impact of thoracic esophageal displacement after lobectomy on the continuity of oral adjuvant chemotherapy."], "weko_shared_id": -1}