Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2023-05-02 |
タイトル |
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タイトル |
Usefulness of intravoxel incoherent motion MRI for visualizing slow cerebrospinal fluid motion |
言語 |
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言語 |
eng |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Cerebrospinal fluid dynamics |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Idiopathic normal pressure hydrocephalus |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Aging |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Intravoxel incoherent motion |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Diffusion-weighted image |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
著者 |
YAMADA, Shigeki
HIRATSUKA, Shinnosuke
OTANI, Tomohiro
II, Satoshi
WADA, Shigeo
OSHIMA, Marie
NOZAKI, Kazuhiko
WATANABE, Yoshiyuki
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著者別名 |
山田, 茂樹
平塚, 真之輔
野﨑, 和彦
渡邉, 嘉之
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抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Background: In the cerebrospinal fluid (CSF) dynamics, the pulsations of cerebral arteries and brain is considered the main driving force for the reciprocating bidirectional CSF movements. However, measuring these complex CSF movements on conventional flow-related MRI methods is difficult. We tried to visualize and quantify the CSF motion by using intravoxel incoherent motion (IVIM) MRI with low multi-b diffusion-weighted imaging. |
抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Methods: Diffusion-weighted sequence with six b values (0, 50, 100, 250, 500, and 1000 s/mm2) was performed on 132 healthy volunteers aged ≥ 20 years and 36 patients with idiopathic normal pressure hydrocephalus (iNPH). The healthy volunteers were divided into three age groups (< 40, 40 to < 60, and ≥ 60 years). In the IVIM analysis, the bi-exponential IVIM fitting method using the Levenberg-Marquardt algorithm was adapted. The average, maximum, and minimum values of ADC, D, D*, and fraction of incoherent perfusion (f) calculated by IVIM were quantitatively measured in 45 regions of interests in the whole ventricles and subarachnoid spaces. |
抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Results: Compared with healthy controls aged ≥ 60 years, the iNPH group had significantly lower mean f values in all the parts of the lateral and 3rd ventricles, whereas significantly higher mean f value in the bilateral foramina of Luschka. In the bilateral Sylvian fossa, which contain the middle cerebral bifurcation, the mean f values increased gradually with increasing age, whereas those were significantly lower in the iNPH group. In the 45 regions of interests, the f values in the bilateral foramina of Luschka were the most positively correlated with the ventricular size and indices specific to iNPH, whereas that in the anterior part of the 3rd ventricle was the most negatively correlated with the ventricular size and indices specific to iNPH. Other parameters of ADC, D, and D* were not significantly different between the two groups in any locations. |
抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Conclusions: The f value on IVIM MRI is useful for evaluating small pulsatile complex motion of CSF throughout the intracranial CSF spaces. Patients with iNPH had significantly lower mean f values in the whole lateral ventricles and 3rd ventricles and significantly higher mean f value in the bilateral foramina of Luschka, compared with healthy controls aged ≥ 60 years. |
書誌情報 |
en : Fluids and Barriers of the CNS
巻 20,
号 1,
発行日 2023-03-10
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出版者 |
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出版者 |
BioMed Central Ltd |
ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
2045-8118 |
PMID |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
PMID |
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関連識別子 |
36899412 |
PMCID |
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識別子タイプ |
URI |
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関連識別子 |
http://www.ncbi.nlm.nih.gov/pmc/articles/pmc9999497/ |
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関連名称 |
PMC9999497 |
DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1186/s12987-023-00415-6 |
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関連名称 |
10.1186/s12987-023-00415-6 |
権利 |
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権利情報 |
© 2023. The Author(s). |
フォーマット |
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内容記述タイプ |
Other |
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内容記述 |
application/pdf |
著者版フラグ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
資源タイプ |
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内容記述タイプ |
Other |
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内容記述 |
Journal Article |