WEKO3
アイテム
Improvement in Decline Rate of Estimated Glomerular Filtration Rate after Febuxostat Treatment in a Fabry Disease Patient with Enzyme Replacement Therapy-resistant Proteinuria.
http://hdl.handle.net/10422/00013452
http://hdl.handle.net/10422/00013452503c5d36-75e3-489e-9b6d-b78bfc13235d
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
internalmedicine.8993-21 (592.4 kB)
|
The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
|
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2022-11-10 | |||||
| タイトル | ||||||
| タイトル | Improvement in Decline Rate of Estimated Glomerular Filtration Rate after Febuxostat Treatment in a Fabry Disease Patient with Enzyme Replacement Therapy-resistant Proteinuria. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Fabry disease | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | hyperuricemia | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | tubular cell damage | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | xanthine oxidase inhibitor | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | urate crystal | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
KUME, Shinji
× KUME, Shinji× YASUDA-YAMAHARA, Mako× IMAMURA-UEHARA, Yoshimi× KUWAGATA, Shogo× YAMAHARA, Kosuke× TAKEDA, Naoko× CHIN-KANASAKI, Masami× KATO, Koichi× OHNO, Seiko× NAKAGAWA, Yoshihisa× MAEGAWA, Hiroshi |
|||||
| 著者別名 |
久米, 真司
× 久米, 真司× 山原, 真子× 上原, 孔美× 桑形, 尚吾× 山原, 康佑× 武田, 尚子× 金崎, 雅美× 加藤, 浩一× 大野, 聖子× 中川, 義久× 前川, 聡 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Fabry disease is an inherited lysosomal disorder caused by mutations in the alpha-galactosidase A gene. We herein report a Fabry disease patient with enzyme replacement therapy (ERT)-resistant proteinuria who showed improvement in the estimated glomerular filtration rate (eGFR) decline rate after uric acid (UA)-lowering therapy. The patient was diagnosed with Fabry disease at 36 years old. After that, even under ERT, proteinuria and eGFR decline persisted. During the clinical course, serum UA levels were elevated with increases in renal tubular damage markers. Febuxostat administration immediately improved tubular damage and prevented further eGFR decline. UA-mediated tubulopathy may become an additional therapeutic target for eGFR decline in Fabry disease. | |||||
| 書誌情報 |
en : Internal medicine (Tokyo, Japan) 巻 61, 号 20, p. 3077-3081, 発行日 2022-10-15 |
|||||
| 出版者 | ||||||
| 出版者 | The Japanese Society of Internal Medicine | |||||
| 別言語の出版者 | ||||||
| 出版者 | 日本内科学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1349-7235 | |||||
| PMID | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 35283375 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.2169/internalmedicine.8993-21 | |||||
| 関連名称 | 10.2169/internalmedicine.8993-21 | |||||
| 権利 | ||||||
| 権利情報 | Ⓒ 2022 The Japanese Society of Internal Medicine | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Journal Article | |||||
