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Lipoprotein Particle Profiles Compared With Standard Lipids in the Association With Subclinical Aortic Valve Calcification in Apparently Healthy Japanese Men.
http://hdl.handle.net/10422/00013034
http://hdl.handle.net/10422/000130341b81cf89-356e-4bcb-9c28-b284e69a1e5d
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
circj.CJ-20-1090 (395.1 kB)
|
This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license.
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-07-05 | |||||
| タイトル | ||||||
| タイトル | Lipoprotein Particle Profiles Compared With Standard Lipids in the Association With Subclinical Aortic Valve Calcification in Apparently Healthy Japanese Men. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Aortic valve calcification (AVC) | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | High-density lipoprotein particles (HDL-p) | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Low-density lipoprotein particles (LDL-p) | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
VU, Thien
× VU, Thien× FUJIYOSHI, Akira× HISAMATSU, Takashi× KADOTA, Aya× ZAID, Maryam× SEGAWA, Hiroyoshi× KONDO, Keiko× TORII, Sayuki× NAKAGAWA, Yoshihisa× SUZUKI, Tomoaki× ASAI, Tohru× MIURA, Katsuyuki× UESHIMA, Hirotsugu |
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| 著者別名 |
藤吉, 朗
× 藤吉, 朗× 久松, 隆史× 門田, 文× 瀬川, 裕佳× 近藤, 慶子× 鳥居, さゆ希× 中川, 義久× 鈴木, 友彰× 浅井, 徹× 三浦, 克之× 上島, 弘嗣 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background: Risk factors for atherosclerotic disease including dyslipidemia have been shown to be associated with aortic valve calcification (AVC). Nuclear magnetic resonance (NMR)-measured lipoprotein particles, low-density and high-density lipoprotein particles (LDL-p, HDL-p) in particular, have emerged as novel markers of atherosclerotic disease; however, whether NMR-measured particles are associated with AVC remains to be determined. This study aimed to examine the association between NMR-based lipoprotein particle measurements and standard lipids with AVC. The primary variables of interest were LDL-p (nmol/L), HDL-p (μmol/L), LDL-cholesterol, and HDL-cholesterol (both in mg/dL).Methods and Results:A community-based random sample of Japanese men aged 40-79 years examined in 2006-2008, in Shiga, Japan was studied. Presence of AVC was defined as an Agatston score >0. Lipoprotein particles were measured using NMR spectroscopy. In the main analysis, multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (95% CIs) for the prevalence of AVC across the higher quartiles of lipids in reference to the lowest ones were obtained. Of 874 participants analyzed, 153 men had AVC. Multivariable-adjusted ORs of prevalent AVC for the highest vs. the lowest quartile were significantly elevated for LDL-p (OR, 2.20; 95% CI: 1.23-3.93) and LDL-cholesterol (OR, 2.16; 95% CI: 1.23-3.78). In contrast, neither HDL-p nor HDL-cholesterol was associated with AVC. |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Conclusions: The association of prevalent AVC with NMR-based LDL-p was comparable to that with LDL-cholesterol. |
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| 書誌情報 |
en : Circulation journal : official journal of the Japanese Circulation Society 巻 85, 号 7, p. 1076-1082, 発行日 2021-06-25 |
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| 出版者 | ||||||
| 出版者 | Japanese Circulation Society | |||||
| 別言語の出版者 | ||||||
| 出版者 | 日本循環器学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1347-4820 | |||||
| PMID | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 34092755 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1253/circj.cj-20-1090 | |||||
| 関連名称 | 10.1253/circj.CJ-20-1090 | |||||
| 権利 | ||||||
| 権利情報 | © 2021, THE JAPANESE CIRCULATION SOCIETY | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | ||||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Journal Article | |||||
