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The Elevation in Preoperative Procalcitonin Is Associated with a Poor Prognosis for Patients Undergoing Resection for Colorectal Cancer.
http://hdl.handle.net/10422/00012878
http://hdl.handle.net/10422/0001287811d04e6d-1558-454f-a25b-05d2dbcf13a0
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
000511908 (328.4 kB)
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This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC). Usage and distribution for commercial purposes requires written permission.
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2020-12-23 | |||||
| タイトル | ||||||
| タイトル | The Elevation in Preoperative Procalcitonin Is Associated with a Poor Prognosis for Patients Undergoing Resection for Colorectal Cancer. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Infection | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Procalcitonin | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Prognostic nutritional index | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Sepsis | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | mGPS | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
MIYAKE, Toru
× MIYAKE, Toru× IIDA, Hiroya× SHIMIZU, Tomoharu× UEKI, Tomoyuki× KOJIMA, Masatsugu× OHTA, Hiroyuki× YAMAGUCHI, Tsuyoshi× KAIDA, Sachiko× MEKATA, Eiji× ENDO, Yoshihiro× TANI, Masaji |
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| 著者別名 |
三宅, 亨
× 三宅, 亨× 飯田, 洋也× 清水, 智治× 植木, 智之× 小島, 正継× 太田, 裕之× 山口, 剛× 貝田, 佐知子× 目片, 英治× 遠藤, 善裕× 谷, 眞至 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background: Procalcitonin (PCT) is a well-known marker for bacterial infection; however, the clinical significance of PCT in the long-term prognosis after colorectal cancer (CRC) surgery remains unclear. |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Methods: This is a retrospective review of 277 patients that underwent CRC surgery to investigate the relationship between preoperative PCT, clinicopathological condition, cancer-specific overall survival (OS), and relapse-free survival (RFS). |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Results: Median follow-up interval was 5.0 years in all patients. Thirty-six patients developed recurrence, and 46 patients died due to recurrences or metastases of CRC. Preoperative PCT levels were highest in Stage IV patients. The cancer-specific OS in patients with Stage IV/PCT ≤0.05 ng/mL was significantly higher than those with Stage IV/PCT >0.05 ng/mL (3 years survival; 42.3 vs. 14.3%, p = 0.0413). On multivariate analysis, gender, TNM classification, and PCT were identified as significant risk factors for cancer-specific OS in patients with Stage I-III CRC. The cancer-specific OS rate of these patients with PCT ≥0.08 ng/mL, compared with PCT <0.08 ng/mL, was significantly decreased (5 years survival; 59.1 vs. 92.7%, p < 0.0001). TNM classification was finally identified as an independent risk factor for cancer-specific RFS in these patients by multivariate analysis. |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Conclusion: High preoperative PCT values in CRC patients appeared to be associated with poor OS but not RFS following surgical treatments. |
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| 書誌情報 |
en : Digestive surgery p. 1-7, 発行日 2020-11-26 |
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| 出版者 | ||||||
| 出版者 | S. Karger AG | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1421-9883 | |||||
| PMID | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 33242873 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1159/000511908 | |||||
| 関連名称 | 10.1159/000511908 | |||||
| 権利 | ||||||
| 権利情報 | © 2020 The Author(s). Published by S. Karger AG, Basel. | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Journal Article | |||||
