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Relationship Between Step Counts and Cerebral Small Vessel Disease in Japanese Men.
http://hdl.handle.net/10422/00012868
http://hdl.handle.net/10422/000128684cb789d4-b9e7-48ea-b9c9-07407bc19d07
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2020-12-08 | |||||
| タイトル | ||||||
| タイトル | Relationship Between Step Counts and Cerebral Small Vessel Disease in Japanese Men. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | aging brain diseases | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | cerebral small vessel diseases | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | exercise | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | white matter hyperintensities | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
MONIRUZZAMAN, Mohammad
× MONIRUZZAMAN, Mohammad× KADOTA, Aya× SEGAWA, Hiroyoshi× KONDO, Keiko× TORII, Sayuki× MIYAGAWA, Naoko× FUJIYOSHI, Akira× HISAMATSU, Takashi× WATANABE, Yoshiyuki× SHIINO, Akihiko× NOZAKI, Kazuhiko× UESHIMA, Hirotsugu× MIURA, Katsuyuki |
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| 著者別名 |
門田, 文
× 門田, 文× 瀬川, 裕佳× 近藤, 慶子× 鳥居, さゆ希× 宮川, 尚子× 藤吉, 朗× 久松, 隆史× 渡邉, 嘉之× 椎野, 顯彦× 野﨑, 和彦× 上島, 弘嗣× 三浦, 克之 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background and purpose: Cerebral small vessel disease (CSVD) is a common subclinical feature of the aging brain. Steps per day may contribute to its prevention. We herein investigated the association between step counts and CSVD in a healthy Japanese male population. |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Methods: We analyzed data from 680 men who were free of stroke and participated in this observational study. Seven-day step counts were assessed at baseline (2006-2008) using a pedometer. CSVD was assessed at follow-ups (2012-2015) based on deep and subcortical white matter hyperintensities (WMHs), periventricular hyperintensities, lacunar infarcts, and cerebral microbleeds on magnetic resonance imaging. Using a logistic regression analysis, we computed the adjusted odds ratios, with 95% CIs, of prevalent CSVD according to quartiles of step counts (reference: Q1). We also investigated the association between step counts and WMH volumes using a quantile regression. |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Results: Steps per day were significantly associated with lower odds ratios, with the lowest at Q3 (8175-10 614 steps/day), of higher (versus low or no burden) deep and subcortical WMHs (odds ratio, 0.52 [95% CI, 0.30-0.89]), periventricular hyperintensities (0.50 [95% CI, 0.29-0.86]), and lacunar infarcts (0.52 [95% CI, 0.30-0.91]) compared with Q1 (≤6060 steps/day) but not cerebral microbleeds. An inverse linear association was observed between step counts and WMH volumes. These associations were independent of age and smoking and drinking status and remained consistent when adjusted for vascular risk factors. |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Conclusions: We found a J-shaped relationship between step counts and prevalent CSVD in healthy Japanese men, with the lowest risk being observed among participants with ≈8000 to 10 000 steps/day. Higher steps were also associated with lower WMH volumes. |
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| 書誌情報 |
en : Stroke 巻 51, 号 12, p. 3584-3591, 発行日 2020-12 |
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| 出版者 | ||||||
| 出版者 | Lippincott Williams and Wilkins | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1524-4628 | |||||
| PMID | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 33148144 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1161/strokeaha.120.030141 | |||||
| 関連名称 | 10.1161/STROKEAHA.120.030141 | |||||
| 権利 | ||||||
| 権利情報 | © 2020 American Heart Association, Inc. | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Journal Article | |||||
