{"created":"2023-06-19T10:43:31.268813+00:00","id":3758,"links":{},"metadata":{"_buckets":{"deposit":"bac9525f-6499-45f6-8866-28e9574ae5f9"},"_deposit":{"created_by":11,"id":"3758","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"3758"},"status":"published"},"_oai":{"id":"oai:shiga-med.repo.nii.ac.jp:00003758","sets":["19:87:88","30:44:71"]},"author_link":["2935","7911","3536","2796","8296","1966","6336","1647","7910","2983","539","7651","156"],"item_4_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"12","bibliographicPageEnd":"3591","bibliographicPageStart":"3584","bibliographicVolumeNumber":"51","bibliographic_titles":[{},{"bibliographic_title":"Stroke","bibliographic_titleLang":"en"}]}]},"item_4_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"門田, 文"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"瀬川, 裕佳"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"近藤, 慶子"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"鳥居, さゆ希"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"宮川, 尚子"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"藤吉, 朗"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"久松, 隆史"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"渡邉, 嘉之"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"椎野, 顯彦"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"野﨑, 和彦"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"上島, 弘嗣"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"三浦, 克之"}],"nameIdentifiers":[{},{},{}]}]},"item_4_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background and purpose:\nCerebral small vessel disease (CSVD) is a common subclinical feature of the aging brain. Steps per day may contribute to its prevention. We herein investigated the association between step counts and CSVD in a healthy Japanese male population. ","subitem_description_type":"Abstract"},{"subitem_description":"Methods:\nWe analyzed data from 680 men who were free of stroke and participated in this observational study. Seven-day step counts were assessed at baseline (2006-2008) using a pedometer. CSVD was assessed at follow-ups (2012-2015) based on deep and subcortical white matter hyperintensities (WMHs), periventricular hyperintensities, lacunar infarcts, and cerebral microbleeds on magnetic resonance imaging. Using a logistic regression analysis, we computed the adjusted odds ratios, with 95% CIs, of prevalent CSVD according to quartiles of step counts (reference: Q1). We also investigated the association between step counts and WMH volumes using a quantile regression. ","subitem_description_type":"Abstract"},{"subitem_description":"Results:\nSteps per day were significantly associated with lower odds ratios, with the lowest at Q3 (8175-10 614 steps/day), of higher (versus low or no burden) deep and subcortical WMHs (odds ratio, 0.52 [95% CI, 0.30-0.89]), periventricular hyperintensities (0.50 [95% CI, 0.29-0.86]), and lacunar infarcts (0.52 [95% CI, 0.30-0.91]) compared with Q1 (≤6060 steps/day) but not cerebral microbleeds. An inverse linear association was observed between step counts and WMH volumes. These associations were independent of age and smoking and drinking status and remained consistent when adjusted for vascular risk factors. ","subitem_description_type":"Abstract"},{"subitem_description":"Conclusions:\nWe found a J-shaped relationship between step counts and prevalent CSVD in healthy Japanese men, with the lowest risk being observed among participants with ≈8000 to 10 000 steps/day. Higher steps were also associated with lower WMH volumes. ","subitem_description_type":"Abstract"}]},"item_4_description_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_4_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Lippincott Williams and Wilkins"}]},"item_4_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"33148144","subitem_relation_type_select":"PMID"}}]},"item_4_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1161/STROKEAHA.120.030141"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1161/strokeaha.120.030141","subitem_relation_type_select":"DOI"}}]},"item_4_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2020 American Heart Association, Inc."}]},"item_4_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1524-4628","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"MONIRUZZAMAN, Mohammad"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KADOTA, Aya"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"SEGAWA, Hiroyoshi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"KONDO, Keiko"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"TORII, Sayuki"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"MIYAGAWA, Naoko"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"FUJIYOSHI, Akira"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"HISAMATSU, Takashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"WATANABE, Yoshiyuki"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"SHIINO, Akihiko"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"NOZAKI, Kazuhiko"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"UESHIMA, Hirotsugu"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"MIURA, Katsuyuki"}],"nameIdentifiers":[{},{},{}]}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"aging brain diseases","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cerebral small vessel diseases","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"exercise","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"white matter hyperintensities","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Relationship Between Step Counts and Cerebral Small Vessel Disease in Japanese Men.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Relationship Between Step Counts and Cerebral Small Vessel Disease in Japanese Men."}]},"item_type_id":"4","owner":"11","path":["71","88"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-12-08"},"publish_date":"2020-12-08","publish_status":"0","recid":"3758","relation_version_is_last":true,"title":["Relationship Between Step Counts and Cerebral Small Vessel Disease in Japanese Men."],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-06-19T11:40:05.387371+00:00"}