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Alteration in endometrial helper T-cell subgroups in chronic endometritis.
http://hdl.handle.net/10422/00012867
http://hdl.handle.net/10422/00012867dac84060-d847-4f06-bb2f-876661574fb2
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2020-12-08 | |||||
| タイトル | ||||||
| タイトル | Alteration in endometrial helper T-cell subgroups in chronic endometritis. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Th1/Th2/Th17/Treg | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | chronic endometritis | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | helper T cell | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | implantation | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | infertility. | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
KITAZAWA, Jun
× KITAZAWA, Jun× KIMURA, Fuminori× NAKAMURA, Akiko× MORIMUNE, Aina× HANADA, Tetsuro× AMANO, Tsukuru× TSUJI, Shunichiro× KASAHARA, Kyoko× SATOOKA, Hiroki× HIRATA, Takako× KUSHIMA, Ryoji× MURAKAMI, Takashi |
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| 著者別名 |
北澤, 純
× 北澤, 純× 木村, 文則× 中村, 暁子× 森宗, 愛菜× 花田, 哲郎× 天野, 創× 辻, 俊一郎× 笠原, 恭子× 里岡, 大樹× 平田, 多佳子× 九嶋, 亮治× 村上, 節 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Problem: The effect of chronic endometritis (CE) on the subpopulation of CD4+ T cells, Th1, Th2, Th17, and regulatory T cells in the endometrium is unknown. |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Method of study: Lymphocytes were isolated from the endometrium of CE patients (n = 12) and non-CE patients (n = 7). The CD4+ T-cell profile was analyzed by flow cytometry and immunofluorescence. |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Results: In the endometrium of CE patients, there were significantly more Th1 cells among CD4+ cells and fewer Th2 cells in comparison to non-CE patients. No marked difference was observed in Th17 cells or Foxp3+ Treg cells. Moreover, the proportion of Th1 cells increased and the proportion of Th2 cells decreased as the number of CD138+ cells increased. Furthermore, when the localization of CD138+ cells and CD4+ cells was examined, CD4+ cells were found to be clustered around CD138+ cells in CE patients. |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Conclusion: The CD4+ T-cell profile in the endometrium is altered in women with CE. This finding may help to clarify the pathophysiology and development of treatment methods for CE. |
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| 書誌情報 |
en : American journal of reproductive immunology (New York, N.Y. : 1989) p. e13372, 発行日 2020-11-06 |
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| 出版者 | ||||||
| 出版者 | John Wiley & Sons Ltd | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1600-0897 | |||||
| PMID | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 33155317 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1111/aji.13372 | |||||
| 関連名称 | 10.1111/aji.13372 | |||||
| 権利 | ||||||
| 権利情報 | © 2020 John Wiley & Sons A/S. | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Journal Article | |||||
