{"created":"2023-06-19T10:43:31.203537+00:00","id":3757,"links":{},"metadata":{"_buckets":{"deposit":"460ca075-c961-48a0-bcd8-a560fd25e017"},"_deposit":{"created_by":11,"id":"3757","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"3757"},"status":"published"},"_oai":{"id":"oai:shiga-med.repo.nii.ac.jp:00003757","sets":["30:273:274","30:66:216","77:263:264","77:280:281"]},"author_link":["7753","564","3912","12","7872","797","7548","802","7755","7754","798","3319"],"item_4_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-11-06","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"e13372","bibliographic_titles":[{},{"bibliographic_title":"American journal of reproductive immunology (New York, N.Y. : 1989)","bibliographic_titleLang":"en"}]}]},"item_4_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"北澤, 純"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"木村, 文則"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"中村, 暁子"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"森宗, 愛菜"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"花田, 哲郎"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"天野, 創"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"辻, 俊一郎"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"笠原, 恭子"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"里岡, 大樹"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"平田, 多佳子"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"九嶋, 亮治"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"村上, 節"}],"nameIdentifiers":[{},{},{}]}]},"item_4_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Problem:\nThe effect of chronic endometritis (CE) on the subpopulation of CD4+ T cells, Th1, Th2, Th17, and regulatory T cells in the endometrium is unknown. ","subitem_description_type":"Abstract"},{"subitem_description":"Method of study:\nLymphocytes were isolated from the endometrium of CE patients (n = 12) and non-CE patients (n = 7). The CD4+ T-cell profile was analyzed by flow cytometry and immunofluorescence. ","subitem_description_type":"Abstract"},{"subitem_description":"Results:\nIn the endometrium of CE patients, there were significantly more Th1 cells among CD4+ cells and fewer Th2 cells in comparison to non-CE patients. No marked difference was observed in Th17 cells or Foxp3+ Treg cells. Moreover, the proportion of Th1 cells increased and the proportion of Th2 cells decreased as the number of CD138+ cells increased. Furthermore, when the localization of CD138+ cells and CD4+ cells was examined, CD4+ cells were found to be clustered around CD138+ cells in CE patients. ","subitem_description_type":"Abstract"},{"subitem_description":"Conclusion:\nThe CD4+ T-cell profile in the endometrium is altered in women with CE. This finding may help to clarify the pathophysiology and development of treatment methods for CE. ","subitem_description_type":"Abstract"}]},"item_4_description_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_4_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"John Wiley & Sons Ltd"}]},"item_4_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"33155317","subitem_relation_type_select":"PMID"}}]},"item_4_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1111/aji.13372"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1111/aji.13372","subitem_relation_type_select":"DOI"}}]},"item_4_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2020 John Wiley & Sons A/S."}]},"item_4_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1600-0897","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"KITAZAWA, Jun"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"KIMURA, Fuminori"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"NAKAMURA, Akiko"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"MORIMUNE, Aina"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"HANADA, Tetsuro"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"AMANO, Tsukuru"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"TSUJI, Shunichiro"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"KASAHARA, Kyoko"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"SATOOKA, Hiroki"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"HIRATA, Takako"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"KUSHIMA, Ryoji"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"MURAKAMI, Takashi"}],"nameIdentifiers":[{},{},{}]}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Th1/Th2/Th17/Treg","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"chronic endometritis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"helper T cell","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"implantation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"infertility.","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Alteration in endometrial helper T-cell subgroups in chronic endometritis.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Alteration in endometrial helper T-cell subgroups in chronic endometritis."}]},"item_type_id":"4","owner":"11","path":["216","264","274","281"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-12-08"},"publish_date":"2020-12-08","publish_status":"0","recid":"3757","relation_version_is_last":true,"title":["Alteration in endometrial helper T-cell subgroups in chronic endometritis."],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-06-19T11:40:06.360441+00:00"}