{"created":"2023-06-19T10:44:05.426640+00:00","id":4465,"links":{},"metadata":{"_buckets":{"deposit":"fdb1373f-856e-4730-9fbd-e08503db2f01"},"_deposit":{"created_by":11,"id":"4465","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"4465"},"status":"published"},"_oai":{"id":"oai:shiga-med.repo.nii.ac.jp:00004465","sets":["30:200:201"]},"author_link":["9336","9333","6474","9345","9346","7413","9350","9351","9329","9338","8466","9342","7237","9349","9337","9330","9332","9335","9347","7314","7412","9344","9331","9343","9334","9341","9340","9339","9348"],"item_4_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-10","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"135","bibliographicPageStart":"129","bibliographicVolumeNumber":"103","bibliographic_titles":[{},{"bibliographic_title":"Parkinsonism & related disorders","bibliographic_titleLang":"en"}]}]},"item_4_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"14202","affiliationNameIdentifierScheme":"kakenhi"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"KADOTANI, Hiroshi","creatorNameLang":"en"},{"creatorName":"角谷, 寛","creatorNameLang":"ja"},{"creatorName":"カドタニ, ヒロシ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"KADOTANI","familyNameLang":"en"},{"familyName":"角谷","familyNameLang":"ja"},{"familyName":"カドタニ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Hiroshi","givenNameLang":"en"},{"givenName":"寛","givenNameLang":"ja"},{"givenName":"ヒロシ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"角, 幸頼"}],"nameIdentifiers":[{},{},{}]}]},"item_4_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_4_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Introduction:\nIdiopathic rapid eye movement sleep behavior disorder (iRBD) is one of the most specific prodromal symptoms of synucleinopathies, including Parkinson's disease (PD) and multiple system atrophy. The Japan Parkinson's Progression Markers Initiative (J-PPMI) was a prospective cohort study conducted in Japanese patients with iRBD to investigate biomarkers for prodromal synucleinopathies. We carried out an initial assessment of the J-PPMI study to reveal the factors correlated with dopamine transporter single-photon emission computed tomography (DaT) and 123I-meta-iodobenzylguanidine (MIBG) myocardial scintigraphy. ","subitem_description_type":"Abstract"},{"subitem_description":"Methods:\nThis cross-sectional study was conducted in 108 patients with iRBD, selected from the J-PPMI study. We divided the patients into four groups based on the MIBG and DaT results. We also recorded the patients' demographics and clinical data. Following PD probability calculation, we examined the biomarkers associated with DaT and MIBG. ","subitem_description_type":"Abstract"},{"subitem_description":"Results:\nNinety-five of the enrolled patients (88%) met the diagnostic criteria for prodromal PD based on the probability score. Only five patients had normal MIBG and DaT. We identified 29 cases with decreased DaT and MIBG, all of whom met the above diagnostic criteria. Both DaT and MIBG were significantly correlated with the Japanese version of the Montreal Cognitive Assessment (MoCA-J) score. ","subitem_description_type":"Abstract"},{"subitem_description":"Conclusion:Both DaT and MIBG are important biomarkers for confirming synucleinopathies and/or staging disease progression. Although 95% of iRBD patients were consistent with the body-first subtype concept, alpha-synuclein pathologies of iRBD might have widespread systemic involvement rather than being confined to the lower brainstem, particularly in patients with reduced MoCA-J scores. ","subitem_description_type":"Abstract"}]},"item_4_description_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_4_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier Ltd."}]},"item_4_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"36113390","subitem_relation_type_select":"PMID"}}]},"item_4_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1016/j.parkreldis.2022.08.011"}],"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.parkreldis.2022.08.011","subitem_relation_type_select":"DOI"}}]},"item_4_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":" © 2022 Elsevier Ltd. All rights reserved. "}]},"item_4_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1873-5126","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"NISHIKAWA, Noriko"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"MURATA, Miho"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"HATANO, Taku"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"MUKAI, Yohei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SAITOH, Yuji"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"SAKAMOTO, Takashi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"HANAKAWA, Takashi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"KAMEI, Yuichi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"TACHIMORI, Hisateru"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"HATANO, Kenji"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"MATSUDA, Hiroshi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"TARUNO, Yosuke"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"SAWAMOTO, Nobukatsu"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"KAJIYAMA, Yuta"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"IKENAKA, Kensuke"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"KAWABATA, Kazuya"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"NAKAMURA, Tomohiko"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"IWAKI, Hirotaka"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"14202","affiliationNameIdentifierScheme":"kakenhi"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"KADOTANI, Hiroshi","creatorNameLang":"en"},{"creatorName":"角谷, 寛","creatorNameLang":"ja"},{"creatorName":"カドタニ, ヒロシ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"KADOTANI","familyNameLang":"en"},{"familyName":"角谷","familyNameLang":"ja"},{"familyName":"カドタニ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Hiroshi","givenNameLang":"en"},{"givenName":"寛","givenNameLang":"ja"},{"givenName":"ヒロシ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"SUMI, Yukiyoshi"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"INOUE, Yuichi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"HAYASHI, Toshihiro"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"IKEUCHI, Takeshi"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"SHIMO, Yasushi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"MOCHIZUKI, Hideki"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"WATANABE, Hirohisa"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"HATTORI, Nobutaka"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"TAKAHASHI, Yuji"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"TAKAHASHI, Ryosuke"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-09-13"}],"displaytype":"detail","filename":"j.parkreldis.2022.08.011.pdf","filesize":[{"value":"592.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"j.parkreldis.2022.08.011","url":"https://shiga-med.repo.nii.ac.jp/record/4465/files/j.parkreldis.2022.08.011.pdf"},"version_id":"24a80701-1dc1-491c-a99a-8b41b6ddde6c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"(123)I-MIBG myocardial scintigraphy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Alpha-synuclein","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Dopamine transporter single-photon emission computed tomography","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Idiopathic rapid eye movement sleep behavior disorder","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Prodromal Parkinson's disease","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Idiopathic rapid eye movement sleep behavior disorder in Japan: An observational study.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Idiopathic rapid eye movement sleep behavior disorder in Japan: An observational study."}]},"item_type_id":"4","owner":"11","path":["201"],"pubdate":{"attribute_name":"公開日","attribute_value":"2023-04-17"},"publish_date":"2023-04-17","publish_status":"0","recid":"4465","relation_version_is_last":true,"title":["Idiopathic rapid eye movement sleep behavior disorder in Japan: An observational study."],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-07-24T11:31:34.019514+00:00"}