{"created":"2023-06-19T10:44:02.877277+00:00","id":4420,"links":{},"metadata":{"_buckets":{"deposit":"dc5050a7-71dc-4914-98cb-8f9f2d65a64d"},"_deposit":{"created_by":11,"id":"4420","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"4420"},"status":"published"},"_oai":{"id":"oai:shiga-med.repo.nii.ac.jp:00004420","sets":["30:66:216"]},"author_link":["7753","564","8766","797","7548","798","7754","8549"],"item_4_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-10-26","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"242","bibliographicPageStart":"237","bibliographicVolumeNumber":"258","bibliographic_titles":[{},{"bibliographic_title":"The Tohoku journal of experimental medicine","bibliographic_titleLang":"en"}]}]},"item_4_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"信田, 侑里"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"辻, 俊一郎"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"北澤, 純"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"花田, 哲郎"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"中村, 暁子"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"全, 梨花"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"天野, 創"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"村上, 節"}],"nameIdentifiers":[{},{},{}]}]},"item_4_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_4_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Chronic inflammation in cesarean scar defect contributes to secondary infertility in women with cesarean scar syndrom; however, it remains unclear about the situation of inflammation in uterine cavity in women with cesarean scar syndrome. This ambidirectional cohort study aimed to explore the effect of inflammation in the uterine cavities of women with cesarean scar syndrome on infertility at a single university hospital. The frequency of chronic endometritis in infertile patients was retrospectively compared between the cesarean scar syndrome group and non-cesarean scar syndrome group. The frequency of endometriosis was also investigated in patients with cesarean scar syndrome who underwent laparoscopy. The level of tumor necrosis factor-α and interleukin-1β in the uterine cavity was prospectively evaluated in the cesarean scar syndrome group and in women with a history of cesarean section (control group) using an enzyme-linked immunosorbent assay. There was a significant difference in the incidence of chronic endometritis between the cesarean scar syndrome and non-cesarean scar syndrome groups (65.8% and 46.0%, respectively, p = 0.0315). Endometriosis was detected in 51 (70%) patients with laparoscopy. Tumor necrosis factor-α and interleukin-1β levels in the cesarean scar syndrome group were significantly higher than those in the control group (p = 0.0002 and p = 0.0217, respectively). Our findings suggest that one cause of secondary infertility in women with cesarean scar syndrome is embryo implantation failure-associated chronic endometritis, endometriosis, and chronic inflammation in the uterine cavity.","subitem_description_type":"Abstract"}]},"item_4_description_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_4_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tohoku University Medical Press"}]},"item_4_publisher_34":{"attribute_name":"別言語の出版者","attribute_value_mlt":[{"subitem_publisher":"東北ジャーナル刊行会"}]},"item_4_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"36244756","subitem_relation_type_select":"PMID"}}]},"item_4_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1620/tjem.2022.J082"}],"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1620/tjem.2022.J082","subitem_relation_type_select":"DOI"}}]},"item_4_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2022 Tohoku University Medical Press "}]},"item_4_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1349-3329","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"NOBUTA, Yuri"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"TSUJI, Shunichiro"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"KITAZAWA, Jun"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"HANADA, Tetsuro"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"NAKAMURA, Akiko"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"ZEN, Rika"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"AMANO, Tsukuru"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"MURAKAMI, Takashi"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-02-01"}],"displaytype":"detail","filename":"tjem.2022.J082.pdf","filesize":[{"value":"1.3 MB"}],"format":"application/pdf","license_note":"This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license.\nThis is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC-BY-NC-ND 4.0). Anyone may download, reuse, copy, reprint, or distribute the article without modifications or adaptations for non-profit purposes if they cite the original authors and source properly. https://creativecommons.org/licenses/by-nc-nd/4.0/","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"tjem.2022.J082","url":"https://shiga-med.repo.nii.ac.jp/record/4420/files/tjem.2022.J082.pdf"},"version_id":"ffba0a09-f174-43e5-b88d-16a63369f951"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"cesarean section","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"chronic","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"endometritis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"infertility","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"scar","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Decreased Fertility in Women with Cesarean Scar Syndrome Is Associated with Chronic Inflammation in the Uterine Cavity.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Decreased Fertility in Women with Cesarean Scar Syndrome Is Associated with Chronic Inflammation in the Uterine Cavity."}]},"item_type_id":"4","owner":"11","path":["216"],"pubdate":{"attribute_name":"公開日","attribute_value":"2023-02-01"},"publish_date":"2023-02-01","publish_status":"0","recid":"4420","relation_version_is_last":true,"title":["Decreased Fertility in Women with Cesarean Scar Syndrome Is Associated with Chronic Inflammation in the Uterine Cavity."],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-06-19T11:08:47.304718+00:00"}