@article{oai:shiga-med.repo.nii.ac.jp:00004365,
 author = {花岡, 淳 and 余田, 誠 and 岡本, 圭伍 and 賀来, 良輔 and 大塩, 恭彦 and HANAOKA, Jun and YODEN, Makoto and OKAMOTO, Keigo and KAKU, Ryosuke and OHSHIO, Yasuhiko},
 issue = {9},
 journal = {Journal of Thoracic Disease},
 month = {Sep},
 note = {Background:
Mediastinal lymph node (LN) dissection during lung resection is essential for accurate staging. Station 4L dissection is anatomically difficult. Therefore, care should be taken to avoid complications. We investigated the importance of mediastinal LN dissection in left upper lobe lung cancer and evaluated intraoperative videos to identify relevant steps during dissection., Methods:
We retrospectively reviewed 151 consecutive patients with left upper lobe lung cancer. Finally, 139 patients were enrolled to examine the survival effects of clinical factors of metastatic LN stations. The association between risk factors or surgical procedures and recurrent laryngeal nerve palsy was analyzed., Results:
LN dissection of the left upper lobe revealed station 4L LN metastasis in nine patients, three of whom were node-negative on mediastinoscopy. Station 4L LN status was confirmed intraoperatively in 12 of 33 patients. Twenty patients had recurrent laryngeal nerve palsy, four of whom were complicated with aspiration pneumonia. Station 4L LN dissection was an independent risk factor for recurrent laryngeal nerve palsy (P=0.03). The use of an energy device near the recurrent laryngeal nerve was a significant risk factor for recurrent laryngeal nerve palsy. Incidentally, pathological N stage ≥2 was an independent prognostic factor for disease-free survival (DFS) (P=0.005) herein., Conclusions:
In patients with left upper lobe lung cancer, pathological N2 disease is an important predictor of recurrence. Therefore, accurate mediastinal LN dissection, including at station 4L, should be performed. We propose to standardize the dissection procedure at each institution to avoid complications, such as recurrent laryngeal nerve palsy., Journal Article},
 pages = {3321--3334},
 title = {Mediastinal lymph node evaluation, especially at station 4L, in left upper lobe lung cancer},
 volume = {14},
 year = {2022}
}