@article{oai:shiga-med.repo.nii.ac.jp:00004304,
 author = {門田, 文 and 鳥居, さゆ希 and 近藤, 慶子 and 中川, 義久 and 上島, 弘嗣 and 三浦, 克之 and AHMED, Sabrina and HISAMATSU, Takashi and KADOTA, Aya and FUJIYOSHI, Akira and SEGAWA, Hiroyoshi and TORII, Sayuki and TAKASHIMA, Naoyuki and KONDO, Keiko and NAKAGAWA, Yoshihisa and UESHIMA, Hirotsugu and MIURA, Katsuyuki},
 issue = {8},
 journal = {Circulation journal : official journal of the Japanese Circulation Society},
 month = {Jul},
 note = {pdf, Background:
Premature atrial contractions (PACs) are predictors of atrial fibrillation, stroke, and cardiovascular mortality. The present study aimed to assess relevant factors for PACs among a general population of Japanese men.Methods and Results: This study conducted a population-based, cross-sectional study among 517 men, aged 40-79 years, with neither apparent myocardial infarction nor atrial fibrillation. 24-h Holter electrocardiography to assess PAC frequency was used. Age, body mass index, height, low-density lipoprotein cholesterol, triglycerides, high-density lipoprotein cholesterol, mean heart rate, diabetes mellitus, hypertension, physical activity, smoking, alcohol consumption, and lipid-lowering therapy were included in multivariable negative binomial regression analyses to assess correlation for the number of PACs per hour. Almost all participants (99%) had at least 1 PAC in 1 h (median number 2.84 PACs per h). In multivariable negative binomial regression after adjusting for all covariates simultaneously, age (relative risk [95% confidence interval], 1.30 [1.08-1.57] per 1-standard deviation [SD] increment), height (1.19 [1.02-1.39] per 1-SD increment), triglycerides (0.79 [0.65-0.97] per 1-SD increment), mean heart rate (0.69 [0.59-0.80] per 1-SD increment), physical activity (0.63 [0.43-0.93]), current smoking (1.69 [1.06-2.69]), current moderate (1.97 [1.23-3.16]) and heavy (1.84 [1.12-3.01]) alcohol consumption were independently associated with PAC frequency., Conclusions:
PAC frequency was independently associated with age, height, smoking, alcohol consumption, heart rate, physical activity, and triglycerides., Journal Article},
 pages = {1298--1306},
 title = {Premature Atrial Contractions and Their Determinants in a General Population of Japanese Men.},
 volume = {86},
 year = {2022}
}