@article{oai:shiga-med.repo.nii.ac.jp:00004285,
 author = {澤山, 裕一 and 門田, 文 and 鳥居, さゆ希 and 近藤, 慶子 and 肥後, 洋祐 and 原田, 亜紀子 and 渡邉, 嘉之 and 中川, 義久 and 三浦, 克之 and 上島, 弘嗣 and SAWAYAMA, Yuichi and HISAMATSU, Takashi and KADOTA, Aya and TORII, Sayuki and KONDO, Keiko and FUJIYOSHI, Akira and HIGO, Yosuke and HARADA, Akiko and WATANABE, Yoshiyuki and NAKAGAWA, Yoshihisa and MIURA, Katsuyuki and UESHIMA, Hirotsugu},
 issue = {7},
 journal = {Journal of hypertension},
 month = {Jul},
 note = {pdf, Objective:
We aimed to investigate the effect of ambulatory blood pressure (BP) on aortic valve calcification (AVC) and coronary artery calcification (CAC), which are subclinical atherosclerotic diseases., Methods:
In this population-based, cross-sectional study, we assessed office BP, mean ambulatory BP (24-h, awake, and asleep), and variability of ambulatory BP, as determined by the coefficient of variation (awake and asleep). AVC and CAC were quantified using an Agatston score (>0) based on computed tomography scanning. We calculated relative risks (RRs) and 95% confidence intervals (CIs) with a 1-standard deviation increment in each BP index for the presence of AVC and CAC using a multivariate-adjusted Poisson regression with robust error variance., Results:
Of 483 participants (mean age: 66.8 years), 154 (31.9%) and 310 (64.2%) had AVC and CAC, respectively. The presence of AVC was associated with office systolic BP (SBP; RR, 1.15; 95% CI, 1.03-1.28), awake diastolic BP (DBP) variability (RR, 1.12; 95% CI, 1.01-1.25), and asleep SBP variability (RR, 1.14; 95% CI, 1.03-1.27). The presence of CAC was associated with office SBP (RR, 1.08; 95% CI, 1.01-1.15), mean 24-h SBP (RR, 1.10; 95% CI, 1.04-1.16), mean awake SBP (RR, 1.11; 95% CI, 1.04-1.17), mean asleep SBP (RR, 1.07; 95% CI, 1.01-1.13), and asleep SBP variability (RR, 1.07; 95% CI, 1.01-1.13)., Conclusion:
These findings highlight the association of ambulatory BP indices with both AVC and CAC, but with different effects on their presences., Journal Article},
 pages = {1344--1351},
 title = {Association of ambulatory blood pressure with aortic valve and coronary artery calcification.},
 volume = {40},
 year = {2022}
}