@article{oai:shiga-med.repo.nii.ac.jp:00004102,
 author = {久松, 隆史 and 門田, 文 and 藤吉, 朗 and 瀬川, 裕佳 and 鳥居, さゆ希 and 高嶋, 直敬 and 近藤, 慶子 and 中川, 義久 and 上島, 弘嗣 and 三浦, 克之 and AHMED, Sabrina and HISAMATSU, Takashi and KADOTA, Aya and FUJIYOSHI, Akira and SEGAWA, Hiroyoshi and TORII, Sayuki and TAKASHIMA, Naoyuki and KONDO, Keiko and NAKAGAWA, Yoshihisa and UESHIMA, Hirotsugu and MIURA, Katsuyuki and Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA) Research Group},
 journal = {The American journal of cardiology},
 month = {Jan},
 note = {Increased ventricular premature complexes (VPCs) are associated with a higher risk of cardiac morbidities. However, little information is available on the risk factors of Western general populations. Therefore, we aimed to assess the frequency and associated factors of VPCs in healthy general Japanese men. We conducted a population-based cross-sectional study in 517 men, aged 40 to 79 years, using 24-hour Holter electrocardiography. Age, body mass index, height, low-density lipoprotein cholesterol, triglycerides, high-density lipoprotein cholesterol, resting heart rate, diabetes mellitus, hypertension, physical activity, smoking, alcohol consumption, lipid-lowering therapy were included in multivariable negative binomial regression to assess independent correlates for the number of VPCs per hour. We observed at least 1 VPC in 1 hour in 429 men (83%). In multivariable negative binomial regression adjusted for all covariates simultaneously, age (risk ratio [95% confidence interval] 1.91 [1.56 to 2.33] per 1-SD increment), height (1.17 [1.04 to 1.49] per 1-SD increment), resting heart rate(1.34 [1.02 to 1.77] per 1-SD increment), diabetes mellitus (2.36 [1.17 to 4.76] ), hypertension (1.90 [1.03 to 3.50]), physical activity (0.67 [0.47 to 0.97] ), current smoking (4.23 [1.86 to 9.60] ), past smoking (2.08 [1.03 to 4.19] ), current light alcohol consumption (0.16 [0.04 to 0.64] ), and lipid-lowering therapy (0.47 [0.23 to 0.96] ) were independently associated with VPCs frequency. In conclusion, VPCs frequency was independently associated with age, height, resting heart rate, diabetes mellitus, hypertension, physical activity, smoking, alcohol consumption, and lipid-lowering therapy., Journal Article},
 title = {Ventricular Premature Complexes and Their Associated Factors in a General Population of Japanese Men.},
 year = {2022}
}