@article{oai:shiga-med.repo.nii.ac.jp:00004090,
 author = {森宗, 愛菜 and 木村, 文則 and 森谷, 鈴子 and 辻, 俊一郎 and 桂, 大輔 and 星山, 貴子 and 中村, 暁子 and 北澤, 純 and 花田, 哲郎 and 天野, 創 and 九嶋, 亮治 and 村上, 節 and MORIMUNE, Aina and KIMURA, Fuminori and MORITANI, Suzuko and TSUJI, Shunichiro and KATSURA, Daisuke and HOSHIYAMA, Takako and NAKAMURA, Akiko and KITAZAWA, Jun and HANADA, Tetsuro and AMANO, Tsukuru and KUSHIMA, Ryoji and MURAKAMI, Takashi},
 journal = {Journal of reproductive immunology},
 month = {Jan},
 note = {pdf, Chronic deciduitis (CD) is slight inflammation of the decidua found during pregnancy. The cause of preeclampsia is thought to be placental hypoplasia, and various theories have been proposed to explain the detailed mechanism; however, its association with decidual inflammation is unclear. A retrospective case control study was conducted in a single university. Subjects were cases who delivered by cesarean section between January 1, 2013 and June 30, 2020 and whose placentas were pathological assessed. CD was diagnosed by CD138 immunostaining of placental decidua tissue, and the perinatal prognosis and incidences of hypertensive disorder of pregnancy and preeclmpsia were examined according to the presence or absence of CD. A logistic regression analysis was performed to evaluate the association between preeclampsia and 11 explanatory variables (10 patient or perinatal background factors and CD). The study population included 76 patients (non-CD, n = 54; CD, n = 22). The rate of preeclampsia was significantly higher in the CD group (P = 0.0006). Patients with CD gave birth at a significantly earlier gestational age (P=0.040) with a lower birth weight (P = 0.001), and a higher rate of LFD (P = 0.005). The Apgar scores at 1 and 5 min and umbilical artery pH were lower (P = 0.0003, 0.021 and 0.002, respectively) in the CD group. The logistic regression analysis revealed that CD was positively associated with preeclampsia. A retrospective examination of the placenta found that patients with CD had a significantly higher incidence of preeclampsia and CD is considered to be a factor that is associated with poor perinatal outcomes., Journal Article, .},
 title = {The association between chronic deciduitis and preeclampsia.},
 volume = {150},
 year = {2022}
}