{"created":"2023-06-19T10:43:44.573016+00:00","id":4037,"links":{},"metadata":{"_buckets":{"deposit":"5339c571-2bdd-4a8a-904e-38cff9269ae4"},"_deposit":{"created_by":11,"id":"4037","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"4037"},"status":"published"},"_oai":{"id":"oai:shiga-med.repo.nii.ac.jp:00004037","sets":["30:204:205"]},"author_link":["8408","6959","696","6759","844","812","629","8218","6765"],"item_4_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-11-16","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{},{"bibliographic_title":"International Journal of Clinical Oncology","bibliographic_titleLang":"en"}]}]},"item_4_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"前平, 博充"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"辻, 喜久"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"飯田, 洋也"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"森, 治樹"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"新田, 信人"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"前川, 毅"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"貝田, 佐知子"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"三宅, 亨"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"谷, 眞至"}],"nameIdentifiers":[{},{},{}]}]},"item_4_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background:\nPreoperative chemotherapy or chemoradiotherapy is a common strategy for treating pancreatic ductal adenocarcinoma (PDAC). This study aimed to assess the association between the therapeutic response in PDAC and tumor blood circulation. ","subitem_description_type":"Abstract"},{"subitem_description":"Methods:\nThe medical records of patients who underwent chemotherapy or chemoradiotherapy prior to pancreatectomy for PDAC were reviewed. Of these, patient data that included three-phase contrast-enhanced computed tomography (CECT) findings before treatments were used in this study. We evaluated the estimated tumor blood flow (eTBF) using CECT. According to the therapeutic histopathological response defined by the Evans classification, patients were divided into poor (grade I/IIa) and good (grade IIb/III/IV) responder groups. The variables, including eTBF, were compared between the two groups. ","subitem_description_type":"Abstract"},{"subitem_description":"Results:\nThirty patients were enrolled in this study. Of these, 13 (43.3%) (grade IIB/III/IV: 8/4/1 patients) were categorized into the good responder group and 17 patients (56.7%) (grade I/IIA: 4/13 patients) were categorized into the poor responder group. eTBF was significantly higher in the good responder group (0.39 s-1 vs. 0.32 s-1, p = 0.007). An eTBF ≥ 0.36 s-1 was found to be an independent predictive factor for the destruction of over 50% of tumor cells (p = 0.036; odds ratio, 9.71; 95% confidence interval, 1.16-81.30). ","subitem_description_type":"Abstract"},{"subitem_description":"Conclusions:\neTBF can be used to predict the therapeutic histopathological response in PDAC prior to treatment. ","subitem_description_type":"Abstract"}]},"item_4_description_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_4_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer Nature"}]},"item_4_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1007/s10147-021-02066-9"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1007/s10147-021-02066-9","subitem_relation_type_select":"DOI"}}]},"item_4_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2021. The Author(s) under exclusive licence to Japan Society of Clinical Oncology."}]},"item_4_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-9625","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"MAEHIRA, Hiromitsu"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"TSUJI, Yoshihisa"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"IIDA, Hiroya"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"MORI, Haruki"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"NITTA, Nobuhito"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MAEKAWA, Takeru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KAIDA, Sachiko"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"MIYAKE, Toru"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"TANI, Masaji"}],"nameIdentifiers":[{},{},{}]}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Computed tomography","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Chemotherapy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Imaging indicator","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Tumor blood flow","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Therapeutic response","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Pancreatic cancer","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Estimated tumor blood flow as a predictive imaging indicator of therapeutic response in pancreatic ductal adenocarcinoma : use of three-phase contrast-enhanced computed tomography","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Estimated tumor blood flow as a predictive imaging indicator of therapeutic response in pancreatic ductal adenocarcinoma : use of three-phase contrast-enhanced computed tomography"}]},"item_type_id":"4","owner":"11","path":["205"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-11-24"},"publish_date":"2021-11-24","publish_status":"0","recid":"4037","relation_version_is_last":true,"title":["Estimated tumor blood flow as a predictive imaging indicator of therapeutic response in pancreatic ductal adenocarcinoma : use of three-phase contrast-enhanced computed tomography"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-06-19T11:20:38.401920+00:00"}