{"created":"2023-06-19T10:43:41.315279+00:00","id":3962,"links":{},"metadata":{"_buckets":{"deposit":"ecc42c8c-f22c-495d-bdc1-adb343ff72d8"},"_deposit":{"created_by":11,"id":"3962","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"3962"},"status":"published"},"_oai":{"id":"oai:shiga-med.repo.nii.ac.jp:00003962","sets":["30:248:249"]},"author_link":["6550","8596","8594","8592","8595","8593"],"item_4_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-07-23","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageStart":"1327","bibliographicVolumeNumber":"11","bibliographic_titles":[{},{"bibliographic_title":"Diagnostics","bibliographic_titleLang":"en"}]}]},"item_4_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"一杉, 正仁"}],"nameIdentifiers":[{},{},{}]}]},"item_4_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"pdf","subitem_description_type":"Other"}]},"item_4_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Patients with coronavirus disease 2019 (COVID-19) develop severe respiratory failure within a short period during the clinical course. It is essential to predict respiratory deterioration in the short term. We investigated the use of inflammatory markers to predict respiratory distress within three days from their analysis in COVID-19 patients. This retrospective observational study included 81 patients admitted with COVID-19. Patients were divided into two groups according to whether the maximum fraction of inspired oxygen (FiO2) for three days from the blood marker measurements was ≥0.4 (high FiO2 group; HFG) or <0.4 (low FiO2 group; LFG). Interleukin-6 (IL-6), C-reactive protein (CRP), lactate dehydrogenase (LDH), white blood cell, D-dimer, and creatinine levels were compared between the two groups. The levels of all markers were significantly higher in HFG patients. Areas under the receiver operating characteristic curve of IL-6, CRP, and LDH had high values of 0.85, 0.82, and 0.81, respectively. The odds ratio of IL-6 which was crude and adjusted for dexamethasone administration initiated before laboratory measurement, showed the high value of 29.1 (5.6–295.6) and 53.9 (4.5–3242.8), respectively. IL-6 can be used as a reliable marker for predicting respiratory illness within three days after assessment. ","subitem_description_type":"Abstract"}]},"item_4_description_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_4_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"MDPI AG"}]},"item_4_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.3390/diagnostics11081327"}],"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.3390/diagnostics11081327","subitem_relation_type_select":"DOI"}}]},"item_4_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2021 by the authors. Licensee MDPI, Basel, Switzerland."}]},"item_4_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2075-4418","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"FUJINO, Mitsuhiro"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"ISHII, Michiyo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TANIGUCHI, Takuya"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"CHIBA, Hiroya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KIMATA, Masaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"HITOSUGI, Masahito"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-08-18"}],"displaytype":"detail","filename":"diagnostics11081327.pdf","filesize":[{"value":"1.0 MB"}],"format":"application/pdf","license_note":"This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"diagnostics11081327","url":"https://shiga-med.repo.nii.ac.jp/record/3962/files/diagnostics11081327.pdf"},"version_id":"d77bc27a-97b0-4e89-828d-ec30487501ee"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"inflammatory marker","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"interleukin-6","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"novel coronavirus disease","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"respiratory failure","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The Value of Interleukin-6 among Several Inflammatory Markers as a Predictor of Respiratory Failure in COVID-19 Patients.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The Value of Interleukin-6 among Several Inflammatory Markers as a Predictor of Respiratory Failure in COVID-19 Patients."}]},"item_type_id":"4","owner":"11","path":["249"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-08-18"},"publish_date":"2021-08-18","publish_status":"0","recid":"3962","relation_version_is_last":true,"title":["The Value of Interleukin-6 among Several Inflammatory Markers as a Predictor of Respiratory Failure in COVID-19 Patients."],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-06-19T11:22:24.489790+00:00"}