{"created":"2023-06-19T10:43:36.706930+00:00","id":3862,"links":{},"metadata":{"_buckets":{"deposit":"4de762fe-c645-4ee8-8fd3-9a1f27993bee"},"_deposit":{"created_by":11,"id":"3862","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"3862"},"status":"published"},"_oai":{"id":"oai:shiga-med.repo.nii.ac.jp:00003862","sets":["19:82:83"]},"author_link":["8505","8506","6410","6506"],"item_4_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-05-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"1103","bibliographicPageStart":"1093","bibliographicVolumeNumber":"16","bibliographic_titles":[{},{"bibliographic_title":"Stem cell reports","bibliographic_titleLang":"en"}]}]},"item_4_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"築山, 智之"}],"nameIdentifiers":[{},{},{}]}]},"item_4_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"pdf","subitem_description_type":"Other"}]},"item_4_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Human development has been studied for over a century, but the molecular mechanisms underlying human embryogenesis remain largely unknown due to technical difficulties and ethical issues. Accordingly, mice have been used as a model for mammalian development and studied extensively to infer human biology based on the conservation of fundamental processes between the two species. As research has progressed, however, species-specific differences in characteristics between rodents and primates have become apparent. Non-human primates (NHPs) have also been used for biomedical research, and are now attracting attention as a model for human development. Here, we summarize primate species from the evolutionary and genomic points of view. Then we review the current issues and progress in gene modification technology for NHPs. Finally, we discuss recent studies on the early embryogenesis of primates and future perspectives.","subitem_description_type":"Abstract"}]},"item_4_description_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_4_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Cell Press"}]},"item_4_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"33979596","subitem_relation_type_select":"PMID"}}]},"item_4_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1016/j.stemcr.2021.03.021"}],"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.stemcr.2021.03.021","subitem_relation_type_select":"DOI"}}]},"item_4_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2021 The Authors. Published by Elsevier Inc. All rights reserved. "}]},"item_4_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2213-6711","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"NAKAMURA, Tomonori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"FUJIWARA, Kohei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SAITOU, Mitinori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TSUKIYAMA, Tomoyuki"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-05-18"}],"displaytype":"detail","filename":"j.stemcr.2021.03.021.pdf","filesize":[{"value":"9.1 MB"}],"format":"application/pdf","license_note":"This is an open access article under the CC BY-NC-ND license \n(http://creativecommons.org/licenses/by-nc-nd/4.0/).","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"j.stemcr.2021.03.021","url":"https://shiga-med.repo.nii.ac.jp/record/3862/files/j.stemcr.2021.03.021.pdf"},"version_id":"c802cbc1-c88d-4ecb-ad56-f12115d5e671"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"development","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"embryogenesis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"gene modification with NHPs","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"non-human primates","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"peri-implantation","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Non-human primates as a model for human development.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Non-human primates as a model for human development."}]},"item_type_id":"4","owner":"11","path":["83"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-05-18"},"publish_date":"2021-05-18","publish_status":"0","recid":"3862","relation_version_is_last":true,"title":["Non-human primates as a model for human development."],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-06-19T11:34:25.393607+00:00"}