{"created":"2023-06-19T10:43:33.552543+00:00","id":3795,"links":{},"metadata":{"_buckets":{"deposit":"b4da602a-4ec8-4f61-8ca9-02ebab8ce9b5"},"_deposit":{"created_by":11,"id":"3795","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"3795"},"status":"published"},"_oai":{"id":"oai:shiga-med.repo.nii.ac.jp:00003795","sets":["30:293:294"]},"author_link":["8029","2890","2792","8028","5038"],"item_4_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-01-25","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{},{"bibliographic_title":"The Journal of dermatology","bibliographic_titleLang":"en"}]}]},"item_4_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"國府, 拓"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"加藤, 威"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"西川, 絢子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"田中, 俊宏"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"藤本, 徳毅"}],"nameIdentifiers":[{},{},{}]}]},"item_4_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"pdf","subitem_description_type":"Other"}]},"item_4_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Trimethoprim-sulfamethoxazole (TMP/SMX) combination is used for the prophylaxis of Pneumocystis pneumonia (PCP). Although TMP/SMX is frequently used in dermatology for cases treated with corticosteroids and/or immunosuppressants, it is often difficult to continue the administration of TMP/SMX due to adverse events. There are only a few reported studies on the prophylaxis of PCP in dermatology. This is the first review focused on adverse events of TMP/SMX among patients with dermatological diseases compared with previous reports. In this study, we retrospectively investigated 132 cases treated with TMP/SMX and examined the adverse events. Adverse events occurred in 32 cases (24.2%) and the incidence in this study was higher than in previous reports. Thrombocytopenia occurred in 17 cases (12.5%), which was the most frequent adverse event. The possible causes of adverse events were that the standard dose of TMP/SMX may be excessive for most Japanese, in addition to the long administration period, and the concomitant use of corticosteroids and/or immunosuppressants in almost all cases. We must consider the risks of PCP and adverse events of TMP/SMX in each case. It is desirable to examine possible administration methods that can be continued by adjusting the dose and interval of TMP/SMX.","subitem_description_type":"Abstract"}]},"item_4_description_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_4_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wiley"}]},"item_4_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"33492693","subitem_relation_type_select":"PMID"}}]},"item_4_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1111/1346-8138.15724"}],"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1111/1346-8138.15724","subitem_relation_type_select":"DOI"}}]},"item_4_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2021 Japanese Dermatological Association"}]},"item_4_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-8138","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"KOKUBU, Hiraku"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"KATO, Takeshi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"NISHIKAWA, Junko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TANAKA, Toshihiro"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"FUJIMOTO, Noriki"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-25"}],"displaytype":"detail","filename":"1346-8138.15724.pdf","filesize":[{"value":"500.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"1346-8138.15724","url":"https://shiga-med.repo.nii.ac.jp/record/3795/files/1346-8138.15724.pdf"},"version_id":"9318b2fa-94de-4db1-88e9-f114a97f91da"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Asians","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"adverse effects","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"antibiotic premedication","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"dermatology","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"trimethoprim-sulfamethoxazole","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Adverse effects of trimethoprim-sulfamethoxazole for the prophylaxis of Pneumocystis pneumonia in dermatology.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Adverse effects of trimethoprim-sulfamethoxazole for the prophylaxis of Pneumocystis pneumonia in dermatology."}]},"item_type_id":"4","owner":"11","path":["294"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-02-10"},"publish_date":"2021-02-10","publish_status":"0","recid":"3795","relation_version_is_last":true,"title":["Adverse effects of trimethoprim-sulfamethoxazole for the prophylaxis of Pneumocystis pneumonia in dermatology."],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-06-19T11:39:08.355368+00:00"}