{"created":"2023-06-19T10:43:32.837103+00:00","id":3782,"links":{},"metadata":{"_buckets":{"deposit":"57245a7e-4961-4a2b-b748-c74cb2d886b1"},"_deposit":{"created_by":11,"id":"3782","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"3782"},"status":"published"},"_oai":{"id":"oai:shiga-med.repo.nii.ac.jp:00003782","sets":["30:62:231"]},"author_link":["2107","184"],"item_4_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-01-06","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{},{"bibliographic_title":"Brain Tumor Pathology","bibliographic_titleLang":"en"}]}]},"item_4_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中洲, 敏"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"中洲, 庸子"}],"nameIdentifiers":[{},{}]}]},"item_4_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The WHO 2016 classification introduced brain invasion as a standalone criterion for grade II meningioma (GIIM). We systematically reviewed studies published after 2000 and performed a PRISMA-compliant meta-analysis of the hazard ratios (HRs) for progression-free survival (PFS) between brain-invasive and noninvasive meningiomas. In five studies that included both benign and higher-grade meningiomas, brain invasion was a significant risk factor for recurrence (HR = 2.45, p = 0.0004). However, in 3 studies comparing \"brain-invasive meningioma with otherwise benign histology (BIOB)\" with grade I meningioma, brain invasion was not a significant predictor of PFS (HR = 1.49, p = 0.23). Among GIIM per the WHO 2000 criteria, brain invasion was a significant predictor of shorter PFS than noninvasive GIIM (HR = 3.40, p = 0.001) but not per the WHO 2016 criteria (HR 1.13, p = 0.54), as the latter includes BIOB. Meta-regression analysis of seven studies of grade II meningioma showed that more frequent BIOB was associated with lower HRs (p < 0.0001). Hence, there is no rationale for brain invasion as a standalone criterion for grade II meningioma, although almost all studies were retrospective and exhibited highly heterogeneous HRs due to differences in brain-tumor interface data availability. ","subitem_description_type":"Abstract"}]},"item_4_description_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_4_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer Nature"}]},"item_4_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"33403457","subitem_relation_type_select":"PMID"}}]},"item_4_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1007/s10014-020-00390-y"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1007/s10014-020-00390-y","subitem_relation_type_select":"DOI"}}]},"item_4_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© The Japan Society of Brain Tumor Pathology 2021"}]},"item_4_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1433-7398","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"NAKASU, Satoshi"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"NAKASU, Yoko"}],"nameIdentifiers":[{},{}]}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Brain invasion","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Meningioma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Meta-analysis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"WHO grade.","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Prognostic significance of brain invasion in meningiomas: systematic review and meta-analysis.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Prognostic significance of brain invasion in meningiomas: systematic review and meta-analysis."}]},"item_type_id":"4","owner":"11","path":["231"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-01-19"},"publish_date":"2021-01-19","publish_status":"0","recid":"3782","relation_version_is_last":true,"title":["Prognostic significance of brain invasion in meningiomas: systematic review and meta-analysis."],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-06-19T11:39:23.137086+00:00"}