{"created":"2023-06-19T10:43:25.662764+00:00","id":3654,"links":{},"metadata":{"_buckets":{"deposit":"d1476422-eaa3-47a5-bc2e-03de4f0e9f17"},"_deposit":{"created_by":11,"id":"3654","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"3654"},"status":"published"},"_oai":{"id":"oai:shiga-med.repo.nii.ac.jp:00003654","sets":["30:227:228","77:321:322","77:78:79"]},"author_link":["314","806","321","675","778","674","8046"],"item_4_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-11-21","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageStart":"Article number 24","bibliographicVolumeNumber":"5","bibliographic_titles":[{},{"bibliographic_title":"Journal of Pharmaceutical Health Care and Sciences","bibliographic_titleLang":"en"}]}]},"item_4_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"若杉, 吉宣"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"野田, 哲史"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"生野, 芳博"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"堀江, 美弥"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"木藤, 克之"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"南口, 仁志"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"寺田, 智祐"}],"nameIdentifiers":[{},{}]}]},"item_4_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background:\nCyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) regimen includes a high dose of prednisolone (100 mg/body), which exhibits an anticancer and antiemetic effect. However, its optimal use for antiemetic therapy has not been established yet. We assessed the efficacy of granisetron plus aprepitant versus granisetron for CHOP or rituximab-CHOP (R-CHOP) regimen-induced nausea and vomiting in malignant lymphoma. ","subitem_description_type":"Abstract"},{"subitem_description":"Methods:\nThis retrospective and observational clinical study included patients who received CHOP or R-CHOP regimen as initiating chemotherapy between July 2010 and March 2016 (N = 39). Patients were assigned to an aprepitant [aprepitant (125 mg on day 1, 80 mg on days 2-3) plus granisetron (3 mg); n = 15] or control regimen group [granisetron (3 mg); n = 24]. Complete response (CR), defined as no vomiting and no use of rescue therapy during overall phase (0-120 h), was the primary endpoint. Secondary endpoints included the time to first vomiting and using rescue medication and complete protection (CP) defined as no vomiting and no retching and/or no nausea and no rescue therapy. The patient records were investigated, and data were retrospectively analyzed. ","subitem_description_type":"Abstract"},{"subitem_description":"Results:\nCR rate CP rates did not significantly differ between the groups during the observation period (80.0% versus 83.3%, p = 1.000; and 80.0% versus 79.2%, p = 1.000, respectively). Additionally, the time to first vomiting and using rescue medication in did not significantly differ between the groups (p = 0.909). ","subitem_description_type":"Abstract"},{"subitem_description":"Conclusions:\nThis study suggests that granisetron alone could be one treatment option in the management of CINV in patients with non-Hodgkin lymphoma receiving CHOP or R-CHOP regimen. ","subitem_description_type":"Abstract"}]},"item_4_description_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_4_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"BioMed Central"}]},"item_4_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"31832222","subitem_relation_type_select":"PMID"}}]},"item_4_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1186/s40780-019-0153-3"}],"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1186/s40780-019-0153-3","subitem_relation_type_select":"DOI"}}]},"item_4_relation_13":{"attribute_name":"PMCID","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"PMC6868793"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.ncbi.nlm.nih.gov/pmc/articles/pmc6868793/","subitem_relation_type_select":"URI"}}]},"item_4_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© The Author(s). 2019. "}]},"item_4_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"20550294","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"WAKASUGI, Yoshinori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"NODA, Satoshi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"IKUNO, Yoshihiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"HORIE, Miya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KITO, Katsuyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MINAMIGUCHI, Hitoshi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"TERADA, Tomohiro"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-08-11"}],"displaytype":"detail","filename":"s40780-019-0153-3.pdf","filesize":[{"value":"417.3 kB"}],"format":"application/pdf","license_note":"This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"s40780-019-0153-3","url":"https://shiga-med.repo.nii.ac.jp/record/3654/files/s40780-019-0153-3.pdf"},"version_id":"f4a0f650-e7c4-421b-9937-b25f4fbe3d82"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Aprepitant","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"CHOP","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Complete protection","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Complete response","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Granisetron","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Granisetron plus aprepitant versus granisetron in preventing nausea and vomiting during CHOP or R-CHOP regimen in malignant lymphoma: a retrospective study.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Granisetron plus aprepitant versus granisetron in preventing nausea and vomiting during CHOP or R-CHOP regimen in malignant lymphoma: a retrospective study."}]},"item_type_id":"4","owner":"11","path":["79","228","322"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-08-11"},"publish_date":"2020-08-11","publish_status":"0","recid":"3654","relation_version_is_last":true,"title":["Granisetron plus aprepitant versus granisetron in preventing nausea and vomiting during CHOP or R-CHOP regimen in malignant lymphoma: a retrospective study."],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-06-19T12:08:36.908677+00:00"}