@article{oai:shiga-med.repo.nii.ac.jp:00003617,
 author = {高相, 真鈴 and 一杉, 正仁 and 中川, 里沙子 and 向所, 賢一 and 森口, 真吾 and 高, 未来 and 杉原, 洋行 and TAKASO, Marin and HITOSUGI, Masahito and NAKAGAWA, Risako and MUKAISHO, Ken-ichi and MORIGUCHI, Shingo and KOH, Mirae and SUGIHARA, Hiroyuki},
 journal = {Journal of forensic sciences},
 month = {Jun},
 note = {To evaluate the usefulness of forensic autopsies in determining latent prostate cancer (PC) prevalence, we examined latent PC prevalence from autopsies and compared our findings between decedents with and without cancer. Data from forensic autopsies performed in Japan from 2004 to 2014 were obtained. For each prostate, histopathological examinations were performed in both the base and the apex sections. Three hundred and seventeen Japanese decedents were selected for analysis. The mean age of decedents was 56.4 ± 17.8 years (range, 14-94 years). Among this population, 39.4% died suddenly of disease and 60.6% died of external causes. Latent PC was identified in 45 (14.2%) decedents, who ranged from 27 to 93 years old (mean, 71.1 ± 12.9 years). The prevalence of clinically significant PC with a Gleason score of 7 or more was 8.8%, and the rate increased with age. Fifteen males had cancers other than PC. The prevalence of overall latent PC was significantly higher for those with cancer compared with those without (40.0% vs. 12.9%; P = 0.003). In this study, the use of forensic autopsy materials provided the opportunity to obtain a more accurate natural history of PC, as the decedents in this situation would have been more likely to have died suddenly while behaving as normal prior to death, and less likely to have been impacted by long-term medical interventions.},
 title = {Forensic Autopsies can Determine Latent Prostate Cancer Prevalence.},
 year = {2020}
}