@article{oai:shiga-med.repo.nii.ac.jp:00003614, author = {郭, 翔志 and 久保, 卓郎 and 木村, 文則 and 中村, 暁子 and 北澤, 純 and 森宗, 愛菜 and 高橋, 顕雅 and 竹林, 明枝 and 高島, 明子 and 九嶋, 亮治 and 村上, 節 and KAKU, Shoji and KUBO, Takuro and KIMURA, Fuminori and NAKAMURA, Akiko and KITAZAWA, Jun and MORIMUNE, Aina and TAKAHASHI, Akimasa and TAKEBAYASHI, Akie and TAKASHIMA, Akiko and KUSHIMA, Ryoji and MURAKAMI, Takashi}, issue = {1}, journal = {BMC Women's Health}, month = {Jun}, note = {Background: The presence of chronic deciduitis (CD) was determined in patients diagnosed with or without chronic endometritis (CE) before pregnancy., Objective: To study the effect of CE on decidua in cases of miscarriage., Methods: Decidual tissue was obtained from the patients who miscarried at the first pregnancy within a year after the diagnosis of the presence or absence of CE. The number and distribution pattern of plasma cells stained with CD138 in decidual tissue in 10 high-power fields (HPFs) was examined. The prevalence of CD diagnosed with four different grade; grade 0, no plasma cell in 10 HPFs, thus Non-CD;grade 1, rare single plasma cells; grade 2, rare clusters or more than 5 single cells total; and grade 3, many plasma cells with more than 5 clusters, were examined and compared between Non-CE and CE., Results: The incidence rate of CD of grade2 + 3 was significantly higher in CE than Non-CE (53.8%; 7/13 vs. 0%; 0/13, P < 0.01). Presence of clusters or a number of plasma cells in 10 HPFs of decidua showed a sensitivity of 53.8%, a specificity of 100%, a positive predictive value of 100%, and a negative predictive value of 68.4% for the diagnosis of CE., Conclusion: Presence of clusters of plasma cells or five or more of plasma cells in decidua was found in more than half of CE, but not found in Non-CE. When CD with cluster or five or more of plasma cells is confirmed histologically in miscarriage decidual tissue, the presence of CE before the pregnancy should be suspected., Journal Article}, title = {Relationship of Chronic Endometritis With Chronic Deciduitis in Cases of Miscarriage.}, volume = {20}, year = {2020} }