@article{oai:shiga-med.repo.nii.ac.jp:00003600,
 author = {井上, 明星 and 新田, 哲久 and 大田, 信一 and 高木, 海 and 今井, 勇伍 and 岩井, 崇泰 and 園田, 明永 and 向所, 賢一 and 村田, 喜代史 and INOUE, Akitoshi and NITTA, Norihisa and OHTA, Shinichi and TAKAKI, Kai and IMAI, Yugo and MISAKI, Sayaka and IWAI, Takayasu and SONODA, Akinaga and MUKAISHO, Ken-ichi and MURATA, Kiyoshi},
 issue = {2},
 journal = {Magnetic Resonance in Medical Sciences},
 month = {May},
 note = {Purpose: 
This study assessed the MRI findings of strangulated small bowel obstruction (SBO) and mesenteric venous occlusion (MVO) in a rabbit model using 3T MRI. 

Materials and methods: 
Twenty rabbits were included in this study. The strangulated SBO and MVO models were generated via surgical procedures in nine rabbits, and sham surgery was performed in two rabbits. The success of generating the models was confirmed via angiographic, macroscopic, and microscopic findings after the surgical procedure. MRI was performed before and 30 min after inducing mesenteric ischemia. T1-weighted images (T1WIs), T2-weighted images (T2WIs), and fat-suppressed T2WIs (FS-T2WIs) were obtained using the BLADE technique, and fat-suppressed T1WIs (FS-T1WIs) were obtained. The signal intensities of the affected bowel before and after the surgical procedures were visually categorized as high, iso, and low intense compared with the findings for the normal bowel wall on all sequences. Bowel wall thickness was measured, and the signal intensity ratio (SI ratio) was calculated using the signal intensities of the bowel wall and psoas muscle. 

Results:
Angiographic, macroscopic, and microscopic findings confirmed that all surgical procedures were successful. The ischemic bowel wall was thicker than the normal bowel. The bowel wall was thicker in the MVO model (3.17 ± 0.55 mm) than in the strangulated SBO model (2.26 ± 0.46 mm). The signal intensity and SI ratio of the bowel wall were significantly higher after the procedure than before the procedure on all sequences in both models. The mesentery adjacent to the ischemic bowel loop exhibited a high signal intensity in all animals on FS-T2WIs. 

Conclusion: 
Non-contrast MRI can be used to evaluate mesenteric ischemia caused by strangulated SBO and MVO. FS-T2WIs represented the best modality for depicting the high signal intensity in the bowel wall and mesentery caused by ischemia.},
 pages = {125--134},
 title = {MR Imaging-based Evaluation of Mesenteric Ischemia Caused by Strangulated Small Bowel Obstruction and Mesenteric Venous Occlusion: An Experimental Study Using Rabbits.},
 volume = {19},
 year = {2020}
}