{"created":"2023-06-19T10:43:10.225616+00:00","id":3331,"links":{},"metadata":{"_buckets":{"deposit":"98f95771-8a3e-4b6f-974e-9f4936e0b2c1"},"_deposit":{"created_by":11,"id":"3331","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"3331"},"status":"published"},"_oai":{"id":"oai:shiga-med.repo.nii.ac.jp:00003331","sets":["30:214:215"]},"author_link":["210","3381","7418","2390","6240","696","6811","339","7417","137","627","629"],"item_4_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-01-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageStart":"e0191044","bibliographicVolumeNumber":"13","bibliographic_titles":[{"bibliographic_title":"PLoS ONE"}]}]},"item_4_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"井上, 明星"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"古川, 顕"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"山本, 寛"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"OHTA, Shinichi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"貝田, 佐知子"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"山口, 剛"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"村田, 聡"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"小幡, 徹"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"谷, 眞至"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"村田, 喜代史"}],"nameIdentifiers":[{},{}]}]},"item_4_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Dai-kenchu-to (TJ-100) is an herbal medicine used to shorten the duration of intestinal transit by accelerating intestinal movement. However, intestinal movement in itself has not been evaluated in healthy volunteers using radiography, fluoroscopy, and radioisotopes because of exposure to ionizing radiation. The purpose of this study was to evaluate the effect of TJ-100 on intestinal motility using cinematic magnetic resonance imaging (cine MRI) with a steady-state free precession sequence. Ten healthy male volunteers received 5 g of either TJ-100 or lactose without disclosure of the identity of the substance. Each volunteer underwent two MRI examinations after taking the substances (TJ-100 and lactose) on separate days. They drank 1200 mL of tap water and underwent cine MRI after 10 min. A steady-state free precession sequence was used for imaging, which was performed thrice at 0, 10, 20, 30, 40, and 50 min. The bowel contraction frequency and distention score were assessed. Wilcoxon signed-rank test was used, and differences were considered significant at a P-value <0.05. The bowel contraction frequency tended to be greater in the TJ-100 group and was significantly different in the ileum at 20 (TJ-100, 8.95 ± 2.88; lactose, 4.80 ± 2.92; P < 0.05) and 50 min (TJ-100, 9.45 ± 4.49; lactose, 4.45 ± 2.65; P < 0.05) between the groups. No significant differences were observed in the bowel distention scores. Cine MRI demonstrated that TJ-100 activated intestinal motility without dependence on ileum distention.","subitem_description_type":"Abstract"}]},"item_4_description_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_4_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Public Library of Science"}]},"item_4_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"29320574","subitem_relation_type_select":"PMID"}}]},"item_4_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1371/journal.pone.0191044","subitem_relation_type_select":"DOI"}}]},"item_4_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":" © 2018 Inoue et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited."}]},"item_4_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1932-6203","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Inoue, Akitoshi"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"FURUKAWA, Akira"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"YAMAMOTO, Hiroshi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"OHTA, Shinichi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Linh, Nguyen Dai Hung"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Syerikjan, Tulyeubai"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KAIDA, Sachiko"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"YAMAGUCHI, Tsuyoshi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"MURATA, Satoshi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"OBATA, Toru"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"TANI, Masaji"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"MURATA, Kiyoshi"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-11-14"}],"displaytype":"detail","filename":"journal.pone.0191044.pdf","filesize":[{"value":"2.2 MB"}],"format":"application/pdf","license_note":" © 2018 Inoue et al. ","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"journal.pone.0191044","url":"https://shiga-med.repo.nii.ac.jp/record/3331/files/journal.pone.0191044.pdf"},"version_id":"af2358c5-cf14-493b-8b6e-74375496e903"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Acceleration of small bowel motility after oral administration of dai-kenchu-to (TJ-100) assessed by cine magnetic resonance imaging.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Acceleration of small bowel motility after oral administration of dai-kenchu-to (TJ-100) assessed by cine magnetic resonance imaging."}]},"item_type_id":"4","owner":"11","path":["215"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-11-14"},"publish_date":"2018-11-14","publish_status":"0","recid":"3331","relation_version_is_last":true,"title":["Acceleration of small bowel motility after oral administration of dai-kenchu-to (TJ-100) assessed by cine magnetic resonance imaging."],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-06-19T11:23:09.758447+00:00"}