{"created":"2023-06-19T10:43:07.517498+00:00","id":3277,"links":{},"metadata":{"_buckets":{"deposit":"ddedbbe8-f478-41c8-8e71-639323371b75"},"_deposit":{"created_by":11,"id":"3277","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"3277"},"status":"published"},"_oai":{"id":"oai:shiga-med.repo.nii.ac.jp:00003277","sets":["30:200:201","30:211:212"]},"author_link":["7314","1875","7315","7249","670","3509","7316","7606","7317","6474","7314","1875","7315","7249","670","3509","7316","7606","7317","6474"],"control_number":"3277","item_4_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-08-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"16","bibliographicVolumeNumber":"1","bibliographic_titles":[{"bibliographic_title":"Sleep Science and Practice"}]}]},"item_4_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"角, 幸頼","creatorNameLang":"ja"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"松尾, 雅博","creatorNameLang":"ja"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"中林, 孝夫","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"増田, 史","creatorNameLang":"ja"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"高橋, 正洋","creatorNameLang":"ja"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"加根村, 隆","creatorNameLang":"ja"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"栗山, 健一","creatorNameLang":"ja"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"山田, 尚登","creatorNameLang":"ja"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"鷹見, 将規","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"14202","affiliationNameIdentifierScheme":"kakenhi"}],"affiliationNames":[{"affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"角谷, 寛","creatorNameLang":"ja"}],"familyNames":[{"familyName":"KADOTANI","familyNameLang":"en"},{"familyName":"角谷","familyNameLang":"ja"},{"familyName":"カドタニ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Hiroshi","givenNameLang":"en"},{"givenName":"寛","givenNameLang":"ja"},{"givenName":"ヒロシ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{},{},{}]}]},"item_4_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background\nThis descriptive study was conducted to examine the changes in the symptom frequency in patients with rapid eye movement (REM) sleep behavior disorder (RBD) without medical intervention, in order to determine the association of RBD symptom frequency with disease duration.\n\nMethods\nData were collected from 70 consecutive RBD patients who visited the Sleep Clinic in Shiga University of Medical Science. RBD symptom frequencies at the first visit to the clinic were quantified based on the reports by the patients and their family members.\nFor quality assurance, patients living alone or those with cognitive decline were excluded. Finally, 50 patients with family-confirmed symptom history were enrolled. The symptom frequencies were converted to a unit that reflects the estimated number of nights in a year affected by RBD (NAR). Using NAR, we observed the relation between RBD symptom frequency and the disease duration.\n\nResults\nOf the 50 patients, 41 were male and 9 were female, consistent with the male-dominant nature of this disease. The mean age at RBD onset was 62.2 ± 9.1 years, and the mean disease duration at the time of visit was 6.0 ± 4.9 years. The median symptom frequency was 50 NAR, with a 1st quantile value of 24 NAR and a 3rd quantile value of 115 NAR. When RBD symptom frequency was plotted against disease duration, we found that the frequency was lowest in the first 2 years of RBD (median, 18; range, 2–29 NAR), and higher frequencies were found in 2-year bin groups from 2 to 8 years after RBD onset (median, 60; range, 50–150 NAR). Intriguingly, after 8 years of RBD, the frequency returned to a level comparable to that in the first 2 years of RBD (median, 50; range, 12–100 NAR).\n\nConclusions\nThere was no association between RBD symptom frequency and disease duration. RBD  linical symptoms could be less prominent when neural damage becomes severe. Therefore, a natural decrease in RBD symptom frequency may be indicative of progression of neurodegeneration.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_4_description_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_4_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"BMC","subitem_publisher_language":"en"}]},"item_4_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1186/s41606-017-0017-4","subitem_relation_type_select":"DOI"}}]},"item_4_relation_48":{"attribute_name":"関係URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"博士論文要旨"}],"subitem_relation_type":"isReferencedBy","subitem_relation_type_id":{"subitem_relation_type_id_text":"http://hdl.handle.net/10422/00012687","subitem_relation_type_select":"HDL"}}]},"item_4_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.","subitem_rights_language":"en"}]},"item_4_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2398-2683","subitem_source_identifier_type":"EISSN"}]},"item_4_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"SUMI, Yukiyoshi","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"MATSUO, Masahiro","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Nakabayashi, Takao","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Masuda, Fumi","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"TAKAHASHI, Masahiro","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"KANEMURA, Takashi","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Kuriyama, Kenichi","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"YAMADA, Naoto","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"TAKAMI, Masanori","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"14202","affiliationNameIdentifierScheme":"kakenhi"}],"affiliationNames":[{"affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"KADOTANI, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-04-27"}],"displaytype":"detail","filename":"s41606-017-0017-4-1.pdf","filesize":[{"value":"537.7 kB"}],"format":"application/pdf","license_note":"© The Author(s) 2017","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"s41606-017-0017-4-1","url":"https://shiga-med.repo.nii.ac.jp/record/3277/files/s41606-017-0017-4-1.pdf"},"version_id":"a12c167e-0b3e-495c-b08c-48f5b63c73ca"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"REM Sleep Behavior Disorder","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Symptom frequency","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Disease duration","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Changes in the symptom frequency of rapid eye movement sleep behavior disorder according to disease duration","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Changes in the symptom frequency of rapid eye movement sleep behavior disorder according to disease duration","subitem_title_language":"en"}]},"item_type_id":"4","owner":"11","path":["201","212"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-04-27"},"publish_date":"2018-04-27","publish_status":"0","recid":"3277","relation_version_is_last":true,"title":["Changes in the symptom frequency of rapid eye movement sleep behavior disorder according to disease duration"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-07-25T03:19:21.385147+00:00"}