{"created":"2023-06-19T10:40:39.164167+00:00","id":179,"links":{},"metadata":{"_buckets":{"deposit":"26324ca2-1237-47bd-b70a-086a1bc3f546"},"_deposit":{"created_by":3,"id":"179","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"179"},"status":"published"},"_oai":{"id":"oai:shiga-med.repo.nii.ac.jp:00000179","sets":["6:7:123:124"]},"author_link":["7606","601","675","674","671","673","670","672"],"item_3_alternative_title_18":{"attribute_name":"その他の言語のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"The challenge to the personalized medicine for psychiatric patients"}]},"item_3_alternative_title_19":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"セイシン シッカン カンジャ ヘノ オーダーメイド イリョウ ヘノ チョウセン ダイ11カイ キソ リンショウ ユウゴウ ノ ガクナイ キョウドウ ケンキュウ ハッピョウカイ"}]},"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-03-14","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"a08","bibliographicPageStart":"a02","bibliographicVolumeNumber":"27","bibliographic_titles":[{"bibliographic_title":"滋賀医科大学雑誌"}]}]},"item_3_description_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Departmental Bulletin Paper","subitem_description_type":"Other"}]},"item_3_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"We found the plasma concentrations of two psychotropics measured by high performance liquid chromatography (HPLC), which might predict the clinical and/or adverse effects in psychiatric patients, in the small preliminary study. The following results were obtained; 1) The higher ratio of clozapine/N-desmethylclozapine concentration might show better clinical response, but the sum of clozapine and N-desmethylclozapine concentration over 1500ng/mL might cause the cognitive impairment in Japanese schizophrenic patients. 2) More than 8 μg/mL of plasma concentration of lamotrigine might be needed to treat in Japanese bipolar disorders. Using simple HPLC methods in daily clinical situation can help psychiatrists in performing the personalized medicine for psychiatric patients.","subitem_description_type":"Other"}]},"item_3_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"滋賀医科大学雑誌編集委員会"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"森田, 幸代"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"高橋, 正洋"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"大久保, 雅則"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"赤羽, 理也"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"上西, 幸治"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"野田, 哲史"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"寺田, 智祐"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"山田, 尚登"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-16"}],"displaytype":"detail","filename":"jsums2701pa02.pdf","filesize":[{"value":"502.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"jsums2701pa02.pdf","url":"https://shiga-med.repo.nii.ac.jp/record/179/files/jsums2701pa02.pdf"},"version_id":"220980f2-edcb-4038-864c-043417b0e33c"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"精神疾患患者へのオーダーメイド医療への挑戦（第11回基礎・臨床融合の学内共同研究発表会）","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"精神疾患患者へのオーダーメイド医療への挑戦（第11回基礎・臨床融合の学内共同研究発表会）"}]},"item_type_id":"3","owner":"3","path":["124"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-04-12"},"publish_date":"2016-04-12","publish_status":"0","recid":"179","relation_version_is_last":true,"title":["精神疾患患者へのオーダーメイド医療への挑戦（第11回基礎・臨床融合の学内共同研究発表会）"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-19T12:16:13.334784+00:00"}