@article{oai:shiga-med.repo.nii.ac.jp:00000179,
 author = {森田, 幸代 and 高橋, 正洋 and 大久保, 雅則 and 赤羽, 理也 and 上西, 幸治 and 野田, 哲史 and 寺田, 智祐 and 山田, 尚登},
 issue = {1},
 journal = {滋賀医科大学雑誌},
 month = {Mar},
 note = {Departmental Bulletin Paper, We found the plasma concentrations of two psychotropics measured by high performance liquid chromatography (HPLC), which might predict the clinical and/or adverse effects in psychiatric patients, in the small preliminary study. The following results were obtained; 1) The higher ratio of clozapine/N-desmethylclozapine concentration might show better clinical response, but the sum of clozapine and N-desmethylclozapine concentration over 1500ng/mL might cause the cognitive impairment in Japanese schizophrenic patients. 2) More than 8 μg/mL of plasma concentration of lamotrigine might be needed to treat in Japanese bipolar disorders. Using simple HPLC methods in daily clinical situation can help psychiatrists in performing the personalized medicine for psychiatric patients.},
 pages = {a02--a08},
 title = {精神疾患患者へのオーダーメイド医療への挑戦（第11回基礎・臨床融合の学内共同研究発表会）},
 volume = {27},
 year = {2014}
}