{"created":"2023-06-19T10:40:38.162745+00:00","id":157,"links":{},"metadata":{"_buckets":{"deposit":"4620bb55-dd5a-4fbc-ae1d-2d8930347b74"},"_deposit":{"created_by":3,"id":"157","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"157"},"status":"published"},"_oai":{"id":"oai:shiga-med.repo.nii.ac.jp:00000157","sets":["6:7:125:126"]},"author_link":["542","534","532","539","298","546","538","531"],"item_3_alternative_title_18":{"attribute_name":"その他の言語のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Development of molecular contrast agent using phage display : MR imaging of mouse pancreatic beta-cells"}]},"item_3_alternative_title_19":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"ファージ ディスプレイホウ ヲ モチイタ ブンシ ヒョウテキ ゾウエイザイ ノ カイハツ ： マウス スイゾウ ノ βサイボウ ノ ゾウエイ （ダイ 9カイ キソ リンショウ ユウゴウ ノ ガクナイ キョウドウ ケンキュウ ハッピョウカイ）（ショウロク） "}]},"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-02-20","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"a10","bibliographicPageStart":"a08","bibliographicVolumeNumber":"26","bibliographic_titles":[{"bibliographic_title":"滋賀医科大学雑誌"}]}]},"item_3_description_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Departmental Bulletin Paper","subitem_description_type":"Other"}]},"item_3_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"We developed molecular contrast agent for mouse pancreatic beta-cells. Peptide targeting beta-cells have been selected byphage display method. For MR contrast, we conjugated the peptide probe with superparamagnetic iron oxide. After tail veininjection of the agent, MR images of normal and streptozotocin-induced diabetic mice were acquired by 7T MR scanner. Thepancreas of the normal mice was well enhanced 30 to 60 minutes after the injection, but the pancreas of diabetic mice was not.These results indicate that the contrast agent has effectively enhance pancreatic beta-cells and has potential for clinical use.","subitem_description_type":"Other"}]},"item_3_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"滋賀医科大学雑誌編集委員会"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"椎野, 顯彦"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"小島, 秀人"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"小松, 直樹"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"小畑, 利之"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"寺島, 智也"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"前川, 聡"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"犬伏, 俊郎"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"柏木, 厚典"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-16"}],"displaytype":"detail","filename":"jsums2601pa08.pdf","filesize":[{"value":"851.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"jsums2601pa08.pdf","url":"https://shiga-med.repo.nii.ac.jp/record/157/files/jsums2601pa08.pdf"},"version_id":"22fb70a0-1fa1-4438-aa81-34362d225df8"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ファージディスプレイ法を用いた分子標的造影剤の開発　：　マウス膵臓のβ細胞の造影（第9回基礎・臨床融合の学内共同研究発表会）（抄録）","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ファージディスプレイ法を用いた分子標的造影剤の開発　：　マウス膵臓のβ細胞の造影（第9回基礎・臨床融合の学内共同研究発表会）（抄録）"}]},"item_type_id":"3","owner":"3","path":["126"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-04-12"},"publish_date":"2016-04-12","publish_status":"0","recid":"157","relation_version_is_last":true,"title":["ファージディスプレイ法を用いた分子標的造影剤の開発　：　マウス膵臓のβ細胞の造影（第9回基礎・臨床融合の学内共同研究発表会）（抄録）"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-19T11:41:23.416425+00:00"}