@article{oai:shiga-med.repo.nii.ac.jp:00000111,
 author = {ABDELALIM, Essam Mohamed and TOOYAMA, Ikuo and 遠山, 育夫},
 issue = {1},
 journal = {滋賀医科大学雑誌},
 month = {},
 note = {The natriuretic peptides (NPs) are a family of related hormones that play important roles inthe cardiovascular homeostasis, cell growth and neuroendocrine functions. Recently, theyhave emerged as potentially important clinical biomarkers in heart failure. The heartsecretes two major natriuretic peptides: atrial natriuretic peptide (ANP) and brainnatriuretic peptide (BNP), while C-type natriuretic peptide (CNP) is mainly secretedfrom the brain and blood vessels. The physiological effects of NPs are initiated bybinding to natriuretic peptide receptors (NPRs), which are widely distributed inseveral organs. This review describes: the expression of natriuretic peptides in thecardiomyocytes differentiated from ES cells and their role in the cardiomyocytedevelopment. We also describe the detailed distribution of NPRs in the centralnervous system and their possible functions in various brain regions.},
 pages = {1--23},
 title = {Natriuretic peptides in embryonic stem cell-derived cardiomyocytes and their receptors in the CNS.},
 volume = {22},
 year = {2009},
 yomi = {トオヤマ, イクオ}
}