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Clinical outcomes of low-dose-rate brachytherapy based radiotherapy for intermediate risk prostate cancer.
http://hdl.handle.net/10422/00012774
http://hdl.handle.net/10422/000127740aa82977-e40b-46e4-89de-29f686e35061
名前 / ファイル | ライセンス | アクション |
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jcb.2020.92405 (240.0 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-08-17 | |||||
タイトル | ||||||
タイトル | Clinical outcomes of low-dose-rate brachytherapy based radiotherapy for intermediate risk prostate cancer. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | brachytherapy | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | intermediate risk | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | low-dose-rate | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | prostate cancer | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
OKAMOTO, Keisei
× OKAMOTO, Keisei× OKUYAMA, Kahori× KOHNO, Naoaki× TSUGAWA, Takuya |
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著者別名 |
岡本, 圭生
× 岡本, 圭生× 奥山, 佳ほり× 河野, 直明× 津川, 拓也 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Purpose: To monitor the outcomes for intermediate-risk prostate cancer patients treated with biologically effective dose (BED) ≥ 200 Gy radiotherapy using low-dose-rate (LDR) brachytherapy. |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Material and methods: Between 2005 and 2016, a total of 397 patients with intermediate-risk prostate cancer were treated by LDR-based radiotherapy with a BED ≥ 200 Gy. Treatments consisted of LDR brachytherapy alone (177 cases) or LDR and external beam radiotherapy (EBRT) (220 cases). Short-term androgen deprivation therapy (ADT) was used in 186 patients (46.9%). The median follow-up period was 72 months (range 29-165 months). Dosimetric parameters and BED were studied in each case. The numbers of intermediate-risk features were: 163 patients with 1 intermediate-risk feature (41%), 169 patients with 2 intermediate-risk features (43%), and 65 patients with 3 intermediate-risk features (16%). A total of 145 cases were diagnosed as having primary Gleason pattern 4: Gleason score 4 + 3 (36.5%). |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Results: Three patients developed biochemical failure, thus providing a 7-year actual biochemical failure-free survival (BFFS) rate of 99.1%. Biochemical failure was observed exclusively in cases with distant metastasis: two cases with lymph node metastasis and one case with bone metastasis, thus yielding a 7-year freedom from clinical failure (FFCF) rate of 99.1%. We observed eight deaths, but there was no death from prostate cancer, thus yielding a 7-year cause-specific survival (CSS) rate of 100%, and an overall survival (OS) rate of 98.4%. |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Conclusions: This study highlights excellent outcomes for intermediate-risk prostate cancer patients, including unfavorable intermediate-risk cases, treated with BED ≥ 200 Gy radiotherapy using LDR brachytherapy. LDR alone with a BED of 200 Gy may be an optimal treatment for both favorable and unfavorable intermediate-risk prostate cancer patients, although a longer follow-up is mandatory to confirm the present findings. |
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書誌情報 |
en : Journal of Contemporary Brachytherapy 巻 12, 号 1, p. 6-11, 発行日 2020-02 |
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出版者 | ||||||
出版者 | Termedia Pub. House | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2081-2841 | |||||
PMID | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 32190064 | |||||
PMCID | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7073334/ | |||||
関連名称 | PMC7073334 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.5114/jcb.2020.92405 | |||||
関連名称 | 10.5114/jcb.2020.92405 | |||||
権利 | ||||||
権利情報 | © 2020 Termedia. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal Article |