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ラット腸管粘膜下血管周囲のセロトニン含有神経の起源に関する免疫組織化学的研究
http://hdl.handle.net/10422/91
http://hdl.handle.net/10422/910bd6afc2-9778-4b09-922e-2e4182e343c9
名前 / ファイル | ライセンス | アクション |
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jsums13p041.pdf (6.1 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-04-12 | |||||
タイトル | ||||||
言語 | ja | |||||
タイトル | ラット腸管粘膜下血管周囲のセロトニン含有神経の起源に関する免疫組織化学的研究 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Immunohistochemical study on the origin of 5HT nerve fibers distributed around the submucosal blood vessels in the rat small intestine | |||||
タイトル | ||||||
言語 | ja-Kana | |||||
タイトル | ラット チョウカン ネンマクカ ケッカン シュウイ ノ セロトニン ガンユウ シンケイ ノ キゲン ニ カンスル メンエキ ソシキ カガクテキ ケンキュウ | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
張, 陽
× 張, 陽× 藤宮, 峯子× 寺田, 信國× 前田, 敏博× 小玉, 正智 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The origin of serotonin nerve fibers distributed around submucosal blood vessels in the rat small intestine was studied by immunohistochemistry. In colchicine- and pargyline-treated animals, serotonin-immunoreactive nerve cell bodies were located in the myentenc plexus, andpositive nerve fibers were widely distributed in the myenteric plexus, submucosal plexus, muscle layer and lamina propria of mucosa. Most remarkably, positive nerve fibers were densely distributed around submucosal blood vessels. Mechanical sympathectomy caused a complete disappearance of perivascular positive fibers, however positive fibers in the lamina propria, submucosa and muscle layers were not affected, Positive cell bodies were not found in the celiac sympathetic ganglia but were found in dorsal root ganglia. In a dorsal root ganglion, serotonin was colocalized with substance P, but not colocalized with calcitonin gene-related peptide m nerve cell bodies. Capsaicin treatment on the celiac sympathetic ganglion induced a simultaneous disappearance of serotonin-, calcitonin gene-related peptide- and substance P-immunoreactive nerve fibers around submucosal blood vessels. These results indicate that serotonin-containingnerve fibers around submucosal blood vessels are of extrinsic origin, and they are primaryafferent derived from dorsal root ganglia. | |||||
言語 | en | |||||
書誌情報 |
ja : 滋賀医科大学雑誌 巻 13, p. 41-48, 発行日 1998-02 |
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出版者 | ||||||
言語 | ja | |||||
出版者 | 滋賀医科大学雑誌刊行会 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10044327 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |