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Minor hallucinations in isolated rapid eye movement sleep behavior disorder indicative of early phenoconversion : A preliminary study.
http://hdl.handle.net/10422/00013158
http://hdl.handle.net/10422/000131582e478b02-ac16-4439-a002-84f0d123d735
名前 / ファイル | ライセンス | アクション |
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ane.13555 (4.4 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||
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公開日 | 2021-12-09 | |||||||||||
タイトル | ||||||||||||
タイトル | Minor hallucinations in isolated rapid eye movement sleep behavior disorder indicative of early phenoconversion : A preliminary study. | |||||||||||
言語 | ||||||||||||
言語 | eng | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | hallucinations | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | neurodegenerative disease | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | REM sleep behavior disorder | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | retrospective study | |||||||||||
資源タイプ | ||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
資源タイプ | journal article | |||||||||||
著者 |
SUMI, Yukiyoshi
× SUMI, Yukiyoshi× UBARA, Ayaka× OZEKI, Yuji× 角谷, 寛
WEKO
6474
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著者別名 |
角, 幸頼
× 角, 幸頼× 乳原, 彩香× 尾関, 裕二× 角谷, 寛
WEKO
6474
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抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | Objectives: Minor hallucinations (MH) are psychotic symptoms that can occur anywhere between prodromal to early Parkinson's disease and after onset of motor problems. MH include visual illusions, presence hallucinations, and passage hallucinations. Isolated rapid eye movement sleep behavior disorder (RBD) is a harbinger of neurodegenerative diseases. We conducted a retrospective cohort study to investigate the clinical characteristics of isolated RBD with MH and the risk of phenoconversion. |
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抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | Materials and methods: We retrospectively analyzed the data of 36 patients with isolated RBD (four females; median age, 75.0 years). We defined cases reporting at least one minor hallucination as RBD with MH. Demographic data and cognitive function were compared between patients with and without MH, and Cox proportional hazards models estimated the risk of phenoconversion. |
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抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | Results: We included 10 (27.8%) patients with MH and 26 (72.2%) without MH. Patients with MH were older, had less dopamine transporter accumulation, more severe autonomic dysfunction, more depressive symptoms, and lower verbal fluency and symbol coding test scores than patients without MH. After follow-up (median, 2.50 years), 13.9% (5/36) of all patients developed phenoconversion (Parkinson's disease, two patients; dementia with Lewy bodies, three patients). The rate of phenoconversion was significantly higher in patients with MH (40.0% vs. 3.8%, p = .005). The Cox proportional hazards model adjusted for age, sex, and disease duration revealed that MH was a significant risk factor for phenoconversion (hazard ratio, 14.72; 95% confidence interval, 1.35-160.5). |
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抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | Conclusions: Minor hallucinations may be utilized as early clinical markers for prodromal estimation of neurodegenerative diseases. |
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書誌情報 |
en : Acta neurologica Scandinavica 発行日 2021-11-23 |
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ISSN | ||||||||||||
収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 1600-0404 | |||||||||||
PMID | ||||||||||||
関連タイプ | isVersionOf | |||||||||||
識別子タイプ | PMID | |||||||||||
関連識別子 | 34816426 | |||||||||||
DOI | ||||||||||||
関連タイプ | isVersionOf | |||||||||||
識別子タイプ | DOI | |||||||||||
関連識別子 | https://doi.org/10.1111/ane.13555 | |||||||||||
関連名称 | 10.1111/ane.13555 | |||||||||||
権利 | ||||||||||||
権利情報 | © 2021 John Wiley & Sons A/S . Published by John Wiley & Sons Ltd. | |||||||||||
フォーマット | ||||||||||||
内容記述タイプ | Other | |||||||||||
内容記述 | ||||||||||||
著者版フラグ | ||||||||||||
出版タイプ | AM | |||||||||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||
資源タイプ | ||||||||||||
内容記述タイプ | Other | |||||||||||
内容記述 | Journal Article |