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Non-human primates as a model for human development.
http://hdl.handle.net/10422/00012972
http://hdl.handle.net/10422/00012972b42d8480-c7e3-4d46-b308-9ccda8cfde14
名前 / ファイル | ライセンス | アクション |
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j.stemcr.2021.03.021 (9.1 MB)
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This is an open access article under the CC BY-NC-ND license
(http://creativecommons.org/licenses/by-nc-nd/4.0/). |
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2021-05-18 | |||||
タイトル | ||||||
タイトル | Non-human primates as a model for human development. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | development | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | embryogenesis | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | gene modification with NHPs | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | non-human primates | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | peri-implantation | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
NAKAMURA, Tomonori
× NAKAMURA, Tomonori× FUJIWARA, Kohei× SAITOU, Mitinori× TSUKIYAMA, Tomoyuki |
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著者別名 |
築山, 智之
× 築山, 智之 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Human development has been studied for over a century, but the molecular mechanisms underlying human embryogenesis remain largely unknown due to technical difficulties and ethical issues. Accordingly, mice have been used as a model for mammalian development and studied extensively to infer human biology based on the conservation of fundamental processes between the two species. As research has progressed, however, species-specific differences in characteristics between rodents and primates have become apparent. Non-human primates (NHPs) have also been used for biomedical research, and are now attracting attention as a model for human development. Here, we summarize primate species from the evolutionary and genomic points of view. Then we review the current issues and progress in gene modification technology for NHPs. Finally, we discuss recent studies on the early embryogenesis of primates and future perspectives. | |||||
書誌情報 |
en : Stem cell reports 巻 16, 号 5, p. 1093-1103, 発行日 2021-05-11 |
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出版者 | ||||||
出版者 | Cell Press | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2213-6711 | |||||
PMID | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 33979596 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.stemcr.2021.03.021 | |||||
関連名称 | 10.1016/j.stemcr.2021.03.021 | |||||
権利 | ||||||
権利情報 | © 2021 The Authors. Published by Elsevier Inc. All rights reserved. | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | ||||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal Article |