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A Prospective Multicenter Observational Study of Venous Thromboembolism after Gastric Cancer Surgery (SHISA-1601).
http://hdl.handle.net/10422/00012930
http://hdl.handle.net/10422/00012930ced712ac-d1ca-45d1-a999-7d3e28b7a232
名前 / ファイル | ライセンス | アクション |
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000514309 (492.8 kB)
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This is an Open Access article licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense), applicable to the online version of the article only. Usage and distribution for commercial purposes requires written permission.
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2021-03-18 | |||||
タイトル | ||||||
タイトル | A Prospective Multicenter Observational Study of Venous Thromboembolism after Gastric Cancer Surgery (SHISA-1601). | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | D-dimer | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Gastrectomy | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Gastric cancer | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Soluble fibrin | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Venous thromboembolism (VTE) | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
KAIDA, Sachiko
× KAIDA, Sachiko× MIYAKE, Toru× MURATA, Satoshi× YAMAGUCHI, Tsuyoshi× TATSUTA, Takeshi× MURAKAMI, Koichiro× OKAUCHI, Hiroshi× NISHIMURA, Shoichi× OHTA, Hiroyuki× TSUCHIHASHI, Hiroshi× KAWASAKI, Masayasu× TAKEBAYASHI, Katsushi× SHIMIZU, Tomoharu× TANI, Masaji |
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著者別名 |
貝田, 佐知子
× 貝田, 佐知子× 三宅, 亨× 村田, 聡× 山口, 剛× 龍田, 健× 村上, 耕一郎× 岡内, 博× 西村, 彰一× 太田, 裕之× 土橋, 洋史× 川崎, 誠康× 竹林, 克士× 清水, 智治× 谷, 眞至 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Introduction: This study aimed to clarify the frequency and risk factors of intercurrent venous thromboembolism (VTE) in patients undergoing major curative gastric cancer surgery. |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Methods: This prospective, multicenter, observational study included patients with gastric cancer who underwent radical gastrectomy at 5 hospitals between June 2016 and May 2018. Patients who were preoperatively administered anticoagulants were excluded. |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Results: A total of 126 patients were eligible to participate. VTE occurred within 9 days postoperatively in 5 cases (4.0%; 2 symptomatic and 3 asymptomatic). Postoperative day (POD) 1 plasma D-dimer and soluble fibrin (SF) levels were significantly higher in the VTE group than in the non-VTE group. Receiver-operating characteristic curve (ROC) analysis indicated a statistically significant ability of POD 1 D-dimer and SF levels to predict postoperative VTE development after gastrectomy; this finding was reflected by an area under the curve (AUC) of 0.97 (95% CI 0.92-1.0) and 0.87 (95% CI 0.74-1.0), respectively. Cutoff values of D-dimer (24.6 µg/mL) and SF (64.1 µg/mL) were determined. Intraoperative blood transfusion (odds ratio [OR] 7.86), POD 1 D-dimer ≥24.6 µg/mL (OR 17.35), and POD 1 SF ≥64.1 µg/mL (OR 19.5) were independent predictive factors for postoperative VTE (p < 0.05). |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Conclusion: VTE occurred in 4.0% patients (1.6% symptomatic and 2.4% asymptomatic) after gastric cancer surgery; however, with an early diagnosis and anticoagulant therapy, no patients experienced progression. Careful observation of patients with a high risk for VTE, including intraoperative blood transfusion and high POD 1 D-dimer or SF levels, would contribute to the early detection of VTE. |
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書誌情報 |
en : European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes p. 1-10, 発行日 2021-03-03 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1421-9921 | |||||
PMID | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 33657552 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1159/000514309 | |||||
関連名称 | 10.1159/000514309 | |||||
権利 | ||||||
権利情報 | © 2021 The Author(s) Published by S. Karger AG, Basel. | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
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出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal Article |