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Adverse effects of trimethoprim-sulfamethoxazole for the prophylaxis of Pneumocystis pneumonia in dermatology.
http://hdl.handle.net/10422/00012905
http://hdl.handle.net/10422/00012905f03c23c5-abde-46f5-8e60-3b7e5284e7a9
名前 / ファイル | ライセンス | アクション |
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1346-8138.15724 (500.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2021-02-10 | |||||
タイトル | ||||||
タイトル | Adverse effects of trimethoprim-sulfamethoxazole for the prophylaxis of Pneumocystis pneumonia in dermatology. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Asians | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | adverse effects | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | antibiotic premedication | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | dermatology | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | trimethoprim-sulfamethoxazole | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
KOKUBU, Hiraku
× KOKUBU, Hiraku× KATO, Takeshi× NISHIKAWA, Junko× TANAKA, Toshihiro× FUJIMOTO, Noriki |
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著者別名 |
國府, 拓
× 國府, 拓× 加藤, 威× 西川, 絢子× 田中, 俊宏× 藤本, 徳毅 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Trimethoprim-sulfamethoxazole (TMP/SMX) combination is used for the prophylaxis of Pneumocystis pneumonia (PCP). Although TMP/SMX is frequently used in dermatology for cases treated with corticosteroids and/or immunosuppressants, it is often difficult to continue the administration of TMP/SMX due to adverse events. There are only a few reported studies on the prophylaxis of PCP in dermatology. This is the first review focused on adverse events of TMP/SMX among patients with dermatological diseases compared with previous reports. In this study, we retrospectively investigated 132 cases treated with TMP/SMX and examined the adverse events. Adverse events occurred in 32 cases (24.2%) and the incidence in this study was higher than in previous reports. Thrombocytopenia occurred in 17 cases (12.5%), which was the most frequent adverse event. The possible causes of adverse events were that the standard dose of TMP/SMX may be excessive for most Japanese, in addition to the long administration period, and the concomitant use of corticosteroids and/or immunosuppressants in almost all cases. We must consider the risks of PCP and adverse events of TMP/SMX in each case. It is desirable to examine possible administration methods that can be continued by adjusting the dose and interval of TMP/SMX. | |||||
書誌情報 |
en : The Journal of dermatology 発行日 2021-01-25 |
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出版者 | ||||||
出版者 | Wiley | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1346-8138 | |||||
PMID | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 33492693 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1111/1346-8138.15724 | |||||
関連名称 | 10.1111/1346-8138.15724 | |||||
権利 | ||||||
権利情報 | © 2021 Japanese Dermatological Association | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | ||||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal Article |