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Isolated systolic hypertension and 29-year cardiovascular mortality risk in Japanese adults aged 30--49 years.
http://hdl.handle.net/10422/00012825
http://hdl.handle.net/10422/00012825486d3813-f621-47bf-97a9-6661c618e21c
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-10-28 | |||||
タイトル | ||||||
タイトル | Isolated systolic hypertension and 29-year cardiovascular mortality risk in Japanese adults aged 30--49 years. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
HISAMATSU, Takashi
× HISAMATSU, Takashi× MIURA, Katsuyuki× OHKUBO, Takayoshi× KADOTA, Aya× KONDO, Keiko× KITA, Yoshikuni× HAYAKAWA, Takehito× KANDA, Hideyuki× OKAMURA, Tomonori× OKAYAMA, Akira× UESHIMA, Hirotsugu |
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著者別名 |
久松, 隆史
× 久松, 隆史× 三浦, 克之× 大久保, 孝義× 門田, 文× 近藤, 慶子× 喜多, 義邦× 神田, 秀幸× 岡村, 智教× 岡山, 明× 上島, 弘嗣 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Objective: The prognostic implication of isolated systolic hypertension (ISH), defined as SBP at least 140 mmHg and DBP less than 90 mmHg, among young-to-middle-aged adults remains controversial. We examined the association of ISH with cardiovascular disease (CVD) risk in adults aged 30-49 years. |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Methods: In a prospective cohort of representative Japanese general populations from the NIPPON DATA80 (1980-2009), we studied 4776 participants (mean age, 39.4 years; 55.4% women) without clinical CVD or antihypertensive medication. Participants were classified as follows: normal blood pressure (BP) (SBP/DBP, <120/<80 mmHg), high-normal BP (120-129/<80 mmHg), elevated BP (130-139/80-89 mmHg), ISH, isolated diastolic hypertension (IDH) (<140/≥90 mmHg), and systolic--diastolic hypertension (SDH) (≥140/≥90 mmHg). |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Results: ISH was observed in 389 (8.1%) participants. During the 29-year follow-up, 115 participants died of CVD, 28 of coronary heart disease, and 49 of stroke. Cox proportional hazards models adjusted for demographics and CVD risk factors showed that participants with ISH had higher risk of CVD mortality than those with normal BP [hazard ratio (confidence interval), 4.10 (1.87-9.03)]. The magnitude of CVD mortality risk related to ISH was comparable with that related to IDH [3.38 (1.31-8.72)] and not as great as that related to SDH [5.41 (2.63-11.14)]. We found significant associations of ISH with coronary and stroke mortality. The association of ISH with CVD mortality was consistent across men and women and those aged 30-39 and 40-49 years. |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Conclusion: ISH among young-to-middle-aged Japanese adults was independently associated with higher risk of CVD mortality later in life. |
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書誌情報 |
en : Journal of hypertension 巻 38, 号 11, p. 2230-2236, 発行日 2020-11 |
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出版者 | ||||||
出版者 | Lippincott Williams & Wilkins | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1473-5598 | |||||
PMID | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 32649629 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1097/hjh.0000000000002533 | |||||
関連名称 | 10.1097/HJH.0000000000002533 | |||||
権利 | ||||||
権利情報 | Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved. | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal Article |