WEKO3
アイテム
{"_buckets": {"deposit": "409d500a-270f-421c-b447-01f0ae4c90c1"}, "_deposit": {"created_by": 11, "id": "3612", "owners": [11], "pid": {"revision_id": 0, "type": "depid", "value": "3612"}, "status": "published"}, "_oai": {"id": "oai:shiga-med.repo.nii.ac.jp:00003612", "sets": ["221"]}, "author_link": ["7989", "7992", "7991", "7993", "538", "7990", "7994"], "item_4_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2020-05-22", "bibliographicIssueDateType": "Issued"}, "bibliographic_titles": [{}, {"bibliographic_title": "Diabetes therapy : research, treatment and education of diabetes and related disorders", "bibliographic_titleLang": "en"}]}]}, "item_4_creator_3": {"attribute_name": "著者別名", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "前川, 聡"}], "nameIdentifiers": [{"nameIdentifier": "538", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "00209363", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=00209363"}, {"nameIdentifier": "0000-0002-4611-8149", "nameIdentifierScheme": "ORCID", "nameIdentifierURI": "https://orcid.org/0000-0002-4611-8149"}]}]}, "item_4_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Introduction:\nThe effectiveness of basal insulin (BI) or glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in providing glycemic control in patients with type 2 diabetes (T2D) in Japanese routine practice is not well known. This real-world observational study evaluated the probability of achieving glycemic control in Japanese patients with T2D uncontrolled by oral antidiabetic drugs (OADs) who initiated BI or GLP-1 RA therapy. ", "subitem_description_type": "Abstract"}, {"subitem_description": "Methods:\nPatients with T2D aged ≥ 18 years initiating BI or GLP-1 RA therapy following treatment with OADs were selected from real-world data (RWD) retrieved from a large electronic medical record database in Japan, using data from 01 January 2010 to 30 June 2019. Patients were required to have glycated hemoglobin (HbA1c) ≥ 7% within 90 days prior to the first prescription of BI or GLP-1 RA. The probability of reaching first HbA1c \u003c 7% was assessed over a 24-month period in cohorts of patients who initiated BI (n = 3477) or GLP-1 RA (n = 780) and in subcohorts by number of OADs at baseline (1, 2, or ≥ 3), HbA1c at baseline (≥ 7 to \u003c 8%, ≥ 8 to \u003c 9%, or ≥ 9%), and age (\u003c 65 or ≥ 65 years). ", "subitem_description_type": "Abstract"}, {"subitem_description": "Results:\nMean (standard deviation) baseline HbA1c was 9.4% (1.8%) and 8.8% (1.4%) in patients initiating BI or GLP-1 RA therapy, respectively. The cumulative probability of achieving glycemic control was 50.1% with BI and 60.3% with GLP-1 RA therapy, respectively, at 12 months, and 60.8% and 66.6%, respectively, at 24 months. Quarterly (3-month intervals) conditional probabilities of achieving glycemic control decreased over time and were \u003c 10% after 12 months. Patients with more OADs or higher HbA1c at baseline had a lower probability of achieving glycemic control. ", "subitem_description_type": "Abstract"}, {"subitem_description": "Conclusion:\nAmong Japanese patients with T2D who initiated BI or GLP-1 RA therapy after treatment with OADs, the probability of reaching first glycemic control diminished over time. Further therapy intensification is warranted in patients who do not achieve glycemic control within 6-12 months with BI or GLP-1 RA, particularly those with high HbA1c or taking multiple OADs. ", "subitem_description_type": "Abstract"}]}, "item_4_description_42": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"subitem_description": "Journal Article", "subitem_description_type": "Other"}]}, "item_4_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Springer Nature"}]}, "item_4_relation_10": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "32445125", "subitem_relation_type_select": "PMID"}}]}, "item_4_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1007/s13300-020-00836-8"}], "subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1007/s13300-020-00836-8", "subitem_relation_type_select": "DOI"}}]}, "item_4_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "©The Author(s) 2020"}]}, "item_4_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1869-6953", "subitem_source_identifier_type": "ISSN"}]}, "item_4_version_type_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "BAXTER, Mike"}], "nameIdentifiers": [{"nameIdentifier": "7989", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "MORIMOTO, Yukiko"}], "nameIdentifiers": [{"nameIdentifier": "7994", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "TAMIWA, Masami"}], "nameIdentifiers": [{"nameIdentifier": "7990", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "HATTORI, Masakatsu"}], "nameIdentifiers": [{"nameIdentifier": "7991", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "PENG, Xuejun Victor"}], "nameIdentifiers": [{"nameIdentifier": "7992", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "LUBWAMA, Robert"}], "nameIdentifiers": [{"nameIdentifier": "7993", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "MAEGAWA, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "538", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "00209363", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=00209363"}, {"nameIdentifier": "0000-0002-4611-8149", "nameIdentifierScheme": "ORCID", "nameIdentifierURI": "https://orcid.org/0000-0002-4611-8149"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-06-23"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "s13300-020-00836-8.pdf", "filesize": [{"value": "1.2 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article\u0027s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article\u0027s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.", "licensetype": "license_free", "mimetype": "application/pdf", "size": 1200000.0, "url": {"label": "s13300-020-00836-8", "url": "https://shiga-med.repo.nii.ac.jp/record/3612/files/s13300-020-00836-8.pdf"}, "version_id": "12b98d79-dfc9-480b-882a-2b9ae37c4b46"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Basal insulin", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "GLP-1 RA", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Real-world evidence", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Type 2 diabetes", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "A Real-World Observational Study Evaluating the Probability of Glycemic Control with Basal Insulin or Glucagon-Like Peptide-1 Receptor Agonist in Japanese Patients with Type 2 Diabetes.", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "A Real-World Observational Study Evaluating the Probability of Glycemic Control with Basal Insulin or Glucagon-Like Peptide-1 Receptor Agonist in Japanese Patients with Type 2 Diabetes."}]}, "item_type_id": "4", "owner": "11", "path": ["221"], "permalink_uri": "http://hdl.handle.net/10422/00012730", "pubdate": {"attribute_name": "公開日", "attribute_value": "2020-06-23"}, "publish_date": "2020-06-23", "publish_status": "0", "recid": "3612", "relation": {}, "relation_version_is_last": true, "title": ["A Real-World Observational Study Evaluating the Probability of Glycemic Control with Basal Insulin or Glucagon-Like Peptide-1 Receptor Agonist in Japanese Patients with Type 2 Diabetes."], "weko_shared_id": -1}
A Real-World Observational Study Evaluating the Probability of Glycemic Control with Basal Insulin or Glucagon-Like Peptide-1 Receptor Agonist in Japanese Patients with Type 2 Diabetes.
http://hdl.handle.net/10422/00012730
http://hdl.handle.net/10422/000127300a629a91-15c7-4a7b-b8d7-7dc64de8714a
名前 / ファイル | ライセンス | アクション |
---|---|---|
s13300-020-00836-8 (1.2 MB)
|
This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2020-06-23 | |||||
タイトル | ||||||
タイトル | A Real-World Observational Study Evaluating the Probability of Glycemic Control with Basal Insulin or Glucagon-Like Peptide-1 Receptor Agonist in Japanese Patients with Type 2 Diabetes. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Basal insulin | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | GLP-1 RA | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Real-world evidence | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Type 2 diabetes | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
BAXTER, Mike
× BAXTER, Mike× MORIMOTO, Yukiko× TAMIWA, Masami× HATTORI, Masakatsu× PENG, Xuejun Victor× LUBWAMA, Robert× MAEGAWA, Hiroshi |
|||||
著者別名 |
前川, 聡
× 前川, 聡 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Introduction: The effectiveness of basal insulin (BI) or glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in providing glycemic control in patients with type 2 diabetes (T2D) in Japanese routine practice is not well known. This real-world observational study evaluated the probability of achieving glycemic control in Japanese patients with T2D uncontrolled by oral antidiabetic drugs (OADs) who initiated BI or GLP-1 RA therapy. |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Methods: Patients with T2D aged ≥ 18 years initiating BI or GLP-1 RA therapy following treatment with OADs were selected from real-world data (RWD) retrieved from a large electronic medical record database in Japan, using data from 01 January 2010 to 30 June 2019. Patients were required to have glycated hemoglobin (HbA1c) ≥ 7% within 90 days prior to the first prescription of BI or GLP-1 RA. The probability of reaching first HbA1c < 7% was assessed over a 24-month period in cohorts of patients who initiated BI (n = 3477) or GLP-1 RA (n = 780) and in subcohorts by number of OADs at baseline (1, 2, or ≥ 3), HbA1c at baseline (≥ 7 to < 8%, ≥ 8 to < 9%, or ≥ 9%), and age (< 65 or ≥ 65 years). |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Results: Mean (standard deviation) baseline HbA1c was 9.4% (1.8%) and 8.8% (1.4%) in patients initiating BI or GLP-1 RA therapy, respectively. The cumulative probability of achieving glycemic control was 50.1% with BI and 60.3% with GLP-1 RA therapy, respectively, at 12 months, and 60.8% and 66.6%, respectively, at 24 months. Quarterly (3-month intervals) conditional probabilities of achieving glycemic control decreased over time and were < 10% after 12 months. Patients with more OADs or higher HbA1c at baseline had a lower probability of achieving glycemic control. |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Conclusion: Among Japanese patients with T2D who initiated BI or GLP-1 RA therapy after treatment with OADs, the probability of reaching first glycemic control diminished over time. Further therapy intensification is warranted in patients who do not achieve glycemic control within 6-12 months with BI or GLP-1 RA, particularly those with high HbA1c or taking multiple OADs. |
|||||
書誌情報 |
en : Diabetes therapy : research, treatment and education of diabetes and related disorders 発行日 2020-05-22 |
|||||
出版者 | ||||||
出版者 | Springer Nature | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1869-6953 | |||||
PMID | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 32445125 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1007/s13300-020-00836-8 | |||||
関連名称 | 10.1007/s13300-020-00836-8 | |||||
権利 | ||||||
権利情報 | ©The Author(s) 2020 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal Article |