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Endometrial Immunity for Embryo Implantation and Pregnancy Establishment.
http://hdl.handle.net/10422/00012619
http://hdl.handle.net/10422/000126199212f439-15eb-483a-9d93-ab235da7e133
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
tjem.250.49 (1.3 MB)
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© 2020 Tohoku University Medical Press
This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC-BY-NC-ND 4.0). Anyone may download, reuse, copy, reprint, or distribute the article without modifications or adaptations for non-profit purposes if they cite the original authors and source properly. https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2020-02-25 | |||||
| タイトル | ||||||
| タイトル | Endometrial Immunity for Embryo Implantation and Pregnancy Establishment. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | decidua | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | implantation | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | lymphocytes | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | regulatory T cells | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Th17 cells | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
KITAZAWA, Jun
× KITAZAWA, Jun× KIMURA, Fuminori× NAKAMURA, Akiko× MORIMUNE, Aina× TAKAHASHI, Akimasa× TAKASHIMA, Akiko× AMANO, Tsukuru× TSUJI, Shunichiro× KAKU, Shoji× KASAHARA, Kyoko× MURAKAMI, Takashi |
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| 著者別名 |
北澤, 純
× 北澤, 純× 木村, 文則× 中村, 暁子× 森宗, 愛菜× 高橋, 顕雅× 髙島, 明子× 天野, 創× 辻, 俊一郎× 郭, 翔志× 笠原, 恭子× 村上, 節 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The uterus is an organ for raising the fetus, and its lumen is lined by the endometrium. The endometrium is an important site for the implantation and maturation of fertilized eggs. The endometrium undergoes repetitive proliferation, maturation (decidualization), and exfoliation changes every menstrual cycle. At the same time, the number and type of endometrial immunocompetent cells vary during the menstrual cycle. At the implantation stage, the immunocompetent cells occupy approximately half of the endometrial cells. Immunocompetent cells normally eliminate pathogenic microorganisms to protect the body; however, they also promote immune tolerance to accept the fetus during pregnancy. The immunocompetent cells in the uterus can perform both these functions. With the establishment of pregnancy, stimuli from the trophoblast (placenta) and fetus can also change the immune environment of the uterus, and pregnancy can be maintained only when the immune system is well adapted to the stimuli of some hormones and the fetus. Immunity for the establishment of pregnancy is not simple because multiple immunocompetent cells are involved in establishing and maintaining pregnancy. To understand the immune mechanisms associated with the establishment of pregnancy, we have to learn about each immune cell. This review, therefore, discusses the roles and distribution of the immunocompetent cells inside the uterus during menstruation and early pregnancy. | |||||
| 書誌情報 |
en : The Tohoku journal of experimental medicine 巻 250, 号 1, p. 49-60, 発行日 2020-01 |
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| 出版者 | ||||||
| 出版者 | TOHOKU UNIVERSITY MEDICAL PRESS | |||||
| 別言語の出版者 | ||||||
| 出版者 | 東北ジャーナル刊行会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1349-3329 | |||||
| PMID | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 31996497 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1620/tjem.250.49 | |||||
| 関連名称 | 10.1620/tjem.250.49 | |||||
| 権利 | ||||||
| 権利情報 | © 2020 Tohoku University Medical Press | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Journal Article | |||||
