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Histopathological explanation of the MRI target sign in extra-axial schwannomas.
http://hdl.handle.net/10422/00012814
http://hdl.handle.net/10422/000128149b9134ad-8956-4584-9b04-09ee48b401ca
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2020-10-15 | |||||
タイトル | ||||||
タイトル | Histopathological explanation of the MRI target sign in extra-axial schwannomas. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
ISHIZAWA, Michihito
× ISHIZAWA, Michihito× OKABE, Hidetoshi× MATSUMOTO, Keiji× MORIMOTO, Shigeru× HUKUDA, Shinsuke× CHANO, Tokuhiro |
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著者別名 |
石澤, 命仁
× 石澤, 命仁× 岡部, 英俊× 森本, 茂× 茶野, 徳宏 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: To better understand the nature of magnetic resonance imaging (MRI) findings in schwannomas, especially in the "target sign" of these findings, the histopathological investigation was performed. |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Methods: The MRI findings were correlated with histopathological features in 22 samples of schwannomas, which were mostly resected from the extremities. The histopathological analyses included alcian blue staining and immunohistochemical staining for S-100 protein, proliferating cell nuclear antigen (PCNA) and epithelial membrane antigen (EMA). |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Results: Seven of the 22 samples of schwannomas of the extremities exhibited target signs including a peripheral zone of homogeneously high signal intensity and a central zone of heterogeneous signal intensity in T2-weighted images. Gadolinium-enhanced T1-weighted images demonstrated a central heterogeneous enhancement and a peripheral ring of homogeneously low signal intensity. Histopathologically, S-100 and PCNA were positive only in the central heterogeneous signal area. In contrast, EMA was only stained on the degenerative epi/perineurium in the peripheral zone. |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Conclusion: In schwannomas of the extremities showing target sign in T2-weighted images, histopathologically, the peripheral areas were suggested to be mucinous degeneration of the epineurium or perineurium, while the central areas were composed of truly neoplastic cells. |
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書誌情報 |
en : Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 発行日 2020-09-30 |
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出版者 | ||||||
出版者 | Elsevier B.V. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1436-2023 | |||||
PMID | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 33011023 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.jos.2020.06.009 | |||||
関連名称 | 10.1016/j.jos.2020.06.009 | |||||
権利 | ||||||
権利情報 | © 2020 Published by Elsevier B.V. on behalf of The Japanese Orthopaedic Association. | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal Article |