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A nationwide, multi-center, retrospective study of symptomatic small bowel stricture in patients with Crohn's disease.
http://hdl.handle.net/10422/00012615
http://hdl.handle.net/10422/000126151b799e73-8ca8-4168-adbd-4955b090f57e
名前 / ファイル | ライセンス | アクション |
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s00535-020-01670-2 (994.2 kB)
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© Japanese Society of Gastroenterology 2020
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-02-12 | |||||
タイトル | ||||||
タイトル | A nationwide, multi-center, retrospective study of symptomatic small bowel stricture in patients with Crohn's disease. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Balloon enteroscope | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Inflammatory bowel disease | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Stenosis | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
BAMBA, Shigeki
× BAMBA, Shigeki× SAKEMI, Ryosuke× FUJII, Toshimitsu× TAKEDA, Teruyuki× FUJIOKA, Shin× TAKENAKA, Kento× KITAMOTO, Hiroki× UMEZAWA, Shotaro× SAKURABA, Hirotake× INOKUCHI, Toshihiro× FUKATA, Norimasa× MIZUNO, Shinta× YAMASHITA, Masaki× SHINZAKI, Shinichiro× TANAKA, Hiroki× TAKEDATSU, Hidetoshi× OZAKI, Ryo× MORIYA, Kei× ISHII, Manabu× KINJO, Tetsu× OZEKI, Keiji× OOI, Makoto× HAYASHI, Ryohei× KAKIMOTO, Kazuki× SHIMODATE, Yuichi× KITAMURA, Kazuya× YAMADA, Akihiro× SONODA, Akira× NISHIDA, Yu× YOSHIOKA, Kyouko× ASHIZUKA, Shinya× TAKAHASHI, Fumiaki× SHIMOKAWA, Toshio× KOBAYASHI, Taku× ANDOH, Akira× HIBI, Toshifumi |
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著者別名 |
馬場, 重樹
× 馬場, 重樹× 安藤, 朗 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | BACKGROUND: Small bowel stricture is one of the most common complications in patients with Crohn's disease (CD). Endoscopic balloon dilatation (EBD) is a minimally invasive treatment intended to avoid surgery; however, whether EBD prevents subsequent surgery remains unclear. We aimed to reveal the factors contributing to surgery in patients with small bowel stricture and the factors associated with subsequent surgery after initial EBD. |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | METHODS: Data were retrospectively collected from surgically untreated CD patients who developed symptomatic small bowel stricture after 2008 when the use of balloon-assisted enteroscopy and maintenance therapy with anti-tumor necrosis factor (TNF) became available. |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | RESULTS: A total of 305 cases from 32 tertiary referral centers were enrolled. Cumulative surgery-free survival was 74.0% at 1 year, 54.4% at 5 years, and 44.3% at 10 years. The factors associated with avoiding surgery were non-stricturing, non-penetrating disease at onset, mild severity of symptoms, successful EBD, stricture length < 2 cm, and immunomodulator or anti-TNF added after onset of obstructive symptoms. In 95 cases with successful initial EBD, longer EBD interval was associated with lower risk of surgery. Receiver operating characteristic analysis revealed that an EBD interval of ≤ 446 days predicted subsequent surgery, and the proportion of smokers was significantly high in patients who required frequent dilatation. |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | CONCLUSIONS: In CD patients with symptomatic small bowel stricture, addition of immunomodulator or anti-TNF and smoking cessation may improve the outcome of symptomatic small bowel stricture, by avoiding frequent EBD and subsequent surgery after initial EBD. |
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書誌情報 |
en : Journal of Gastroenterology 巻 55, 号 6, p. 615-626, 発行日 2020-01-27 |
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出版者 | ||||||
出版者 | Springer Nature | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1435-5922 | |||||
PMID | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 31989252 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1007/s00535-020-01670-2 | |||||
関連名称 | 10.1007/s00535-020-01670-2 | |||||
権利 | ||||||
権利情報 | © Japanese Society of Gastroenterology 2020 | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal Article |