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Blood pressure categories and long-term risk of cardiovascular disease by age groups in Japanese men and women
http://hdl.handle.net/10422/10011
http://hdl.handle.net/10422/1001106363d3d-7454-47ff-a213-32cdfd50c6b7
名前 / ファイル | ライセンス | アクション |
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hr.2012.87.pdf (201.9 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2015-05-21 | |||||
タイトル | ||||||
タイトル | Blood pressure categories and long-term risk of cardiovascular disease by age groups in Japanese men and women | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
FUJIYOSHI, Akira
× FUJIYOSHI, Akira× OHKUBO, Takayoshi× MIURA, Katsuyuki× MURAKAMI, Yoshitaka× NAGASAWA, Shin-Ya× OKAMURA, Tomonori× UESHIMA, Hirotsugu |
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著者別名 |
藤吉, 朗
× 藤吉, 朗× 三浦, 克之× 上島, 弘嗣 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Blood pressure (BP) categories defined by systolic BP (SBP) and diastolic BP (DBP) are commonly used. However, the BP category-specific risk of cardiovascular disease (CVD) has not been thoroughly investigated in different age groups. The aim of this study was to assess long-term CVD risk and its impact according to BP categories and age group. Pooling individual data from 10 cohorts, we studied 67 309 Japanese individuals (40-89 years old) who were free of CVD at baseline: we categorized them as belonging to three age groups: 'middle-aged' (40-64 years), 'elderly' (65-74 years) and 'very elderly' (75-89 years). BP was classified according to the 2009 Japanese Society of Hypertension Guidelines. Cox models were used to estimate adjusted hazard ratios for CVD deaths. We observed 1944 CVD deaths over a mean follow-up of 10.2 years. In all age groups, the overall relationship between BP category and CVD risk was positive, with a greater strength observed for younger age groups. We observed a trend of increased risk from SBP/DBP ≥ 130/85 mm Hg in the very elderly, and a significant increase from SBP/DBP ≥ 120/80 mm Hg in the other age groups. The population attributable fractions (PAFs) of CVD death in reference to the SBP/DBP<120/80 mm Hg category ranged from 23.4% in the very elderly to 60.3% in the middle-aged. We found an overall graded increase in CVD risk with higher BP category in the very elderly. The PAFs suggest that keeping BP levels low is an important strategy for primary CVD prevention, even in an elderly population. | |||||
書誌情報 |
Hypertension research 巻 35, 号 9, p. 947-953, 発行日 2012-09 |
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出版者 | ||||||
出版者 | Nature Publishing Group | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10847079 | |||||
PMID | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 22739419 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1038/hr.2012.87 | |||||
関連名称 | 10.1038/hr.2012.87 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | ||||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal Article |