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Distinct localization of peripheral and central types of choline acetyltransferase in the rat cochlea.
http://hdl.handle.net/10422/7512
http://hdl.handle.net/10422/751209b43c00-a478-4684-917c-7ae4325ac78b
名前 / ファイル | ライセンス | アクション |
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46_13021.pdf (1.2 MB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||||
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公開日 | 2014-11-13 | |||||||
タイトル | ||||||||
言語 | en | |||||||
タイトル | Distinct localization of peripheral and central types of choline acetyltransferase in the rat cochlea. | |||||||
言語 | ||||||||
言語 | eng | |||||||
キーワード | ||||||||
言語 | en | |||||||
主題Scheme | Other | |||||||
主題 | acetylcholine | |||||||
キーワード | ||||||||
言語 | en | |||||||
主題Scheme | Other | |||||||
主題 | cholinergic neurons | |||||||
キーワード | ||||||||
言語 | en | |||||||
主題Scheme | Other | |||||||
主題 | choline acetyltransferase | |||||||
キーワード | ||||||||
言語 | en | |||||||
主題Scheme | Other | |||||||
主題 | cochlear nervous system | |||||||
キーワード | ||||||||
言語 | en | |||||||
主題Scheme | Other | |||||||
主題 | spiral ganglion | |||||||
資源タイプ | ||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||
資源タイプ | doctoral thesis | |||||||
アクセス権 | ||||||||
アクセス権 | open access | |||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||
著者 |
KITANISHI, Tsuyoshi
× KITANISHI, Tsuyoshi
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抄録 | ||||||||
内容記述タイプ | Abstract | |||||||
内容記述 | We previously discovered a splice variant of choline acetyltransferase (ChAT) mRNA, and designated the variant protein pChAT because of its preferential expression in peripheral neuronal structures. In this study, we examined the immunohistochemical localization of pChAT in rat cochlea and compared the distribution pattern to those of common ChAT (cChAT) and acetylcholinesterase. Some neuronal cell bodies and fibers in the spiral ganglia showed immunoreactivity for pChAT, predominantly the small spiral ganglion cells, indicating outer hair cell type II neurons. In contrast, cChAT- and acetylcholinesterase-positive structures were localized to fibers and not apparent in ganglion cells. After ablation of the cochlear nuclei, many pChAT-positive cochlear nerve fibers became clearly visible, whereas fibers immunopositive for cChAT and acetylcholine esterase disappeared. These results suggested that pChAT and cChAT are localized in different systems of the rat cochlea; pChAT in the afferent and cChAT in the efferent structures. | |||||||
言語 | en | |||||||
学位名 | ||||||||
言語 | ja | |||||||
学位名 | 博士(医学) | |||||||
学位授与機関 | ||||||||
学位授与機関識別子Scheme | kakenhi | |||||||
学位授与機関識別子 | 14202 | |||||||
言語 | ja | |||||||
学位授与機関名 | 滋賀医科大学 | |||||||
学位授与年度 | ||||||||
内容記述タイプ | Other | |||||||
内容記述 | 平成25年度 | |||||||
言語 | ja | |||||||
学位授与年月日 | ||||||||
学位授与年月日 | 2014-03-10 | |||||||
学位授与番号 | ||||||||
学位授与番号 | 乙第403号 | |||||||
書誌情報 |
en : Acta Histochemica et Cytochemica 巻 46, 号 5, p. 145-152, 発行日 2013-10-30 |
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出版者 | ||||||||
言語 | en | |||||||
出版者 | Japan Society of Histochemistry and Cytochemistry | |||||||
NCID | ||||||||
収録物識別子タイプ | NCID | |||||||
収録物識別子 | AA1202220X | |||||||
権利 | ||||||||
権利情報 | 当論文の著作権は日本組織細胞化学会が有する | |||||||
著者版フラグ | ||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
ISSN | ||||||||
収録物識別子タイプ | PISSN | |||||||
収録物識別子 | 0044-5991 | |||||||
PMID | ||||||||
識別子タイプ | PMID | |||||||
関連識別子 | 24194628 | |||||||
DOI | ||||||||
識別子タイプ | DOI | |||||||
関連識別子 | 10.1267/ahc.13021 | |||||||
資源タイプ | ||||||||
内容記述タイプ | Other | |||||||
内容記述 | Thesis or Dissertation |